Dear Doctor,I feel like my ability to distance myself and observe my own thoughts—specifically my metacognition, or the "observer effect"—has become very weak. Even when I practice mindfulness, I am unable to experience this state. In the past, I used mindfulness very effectively to manage and tackle procrastination.Could this difficulty be because my DLPFC (Dorsolateral Prefrontal Cortex) is not functioning properly?Also, how does the Mirtazapine affect my metacognition? Ii don't use this medicine now almost two yr only take one dose 7.5mg that really spike my anxiety level high i stopped it understand that at a low dose, Mirtazapine causes a histamine-1 receptor blockade, which might slow down dlPFC activity. Is there any way or alternative clinical method to reverse or clear this specific receptor blockade?Finally, are there any specialized medical checkups or diagnostic tests available to evaluate the current working condition and functional state of my DLPFC
My mother is having deep stress and in deep pain from a medical debridement on her foot ulcer. She has had no sleep from the past 4 days and needs help.
Kindly suggest or advice how to go about this from here.
My brother has some issues like he would don't like to meet people and he easily angery. Never talk politely...he suffering this kind of problem from last 3-4 year
Hi. I'm suffering from anxiety and depression since 2023 and I'm on medication . That i stopped taking since one month. Yesterday the doctor gave me a sedative medicine to sleep. It was good. But I'm feeling like my throat is sinking and I'm getting startled from little things now. Is this normal?
I was on petril beta 20 for 3 months and betacap 20 for 1 months and cloba 5 mg in half for 1 months then I changed to another doctor who prescribe me pari cr12.5 mg and clonotril 0.25 mg for ten days but I was iregular in taking medicines I only took 5 tab and 1 or 2 tab of clonotril and till now its been 4 weeks my doctor again gv me pari cr 12.5 mg and clonotril 0.25 mg and on this period my symptoms were so severe as my head was like to explode and bursts I don't know what to do as he has again prescribed me benzodiazepine..will i be able to leave benzodiazepine