Hello Doctor, my mother has ovarian cancer and has completed 4 cycles of neoadjuvant chemotherapy with very good response (CA-125 reduced from 273 to 11). Her treating team is now planning interval cytoreductive surgery with HIPEC.
We would like to take an expert opinion specifically regarding whether HIPEC is truly necessary/beneficial in her case, considering the additional recovery burden and cost. Could you please help us in deciding if HIPEC would be necessary and effective ?
Thank you.
Hello Doctor,
Seeking your opinion regarding a 71-year-old patient diagnosed with NSCLC favor squamous cell carcinoma (P40 diffuse positive, TTF1 negative) involving the right upper lobe. PET-CT shows a spiculated RUL lesion approx. 3.0 × 4.7 × 4.0 cm with SUV max 16.58. Mildly FDG-avid hilar/paratracheal nodes (SUV ~4.2) with some calcification noted. EBUS/TBNA from stations 4R, 7 and 11L showed no evidence of malignancy. Current staging documented as cT2bN1M0 (Stage IIB). Proposed plan is neoadjuvant chemotherapy followed by reassessment for surgery.
Would appreciate guidance on:
1. Whether chemo + surgery appears the optimal curative-intent approach in this case.
2. Whether adding immunotherapy to neoadjuvant chemotherapy would significantly improve outcomes.
3. Whether current imaging/EBUS findings sufficiently support N1 staging or need further nodal evaluation.
Thank you.
I was undergoing IVF treatment which started in 2024 as part of my pre-IVF assessment. I was given a diagnostics hysteroscopy that revealed that I had hyperplasia without atypia in 2024. I don't remember that my doctor was concerned during that time and the only treatment that I was given was Crina 10 for 10 days for my spotting in leutal phase. Now I this year. I am due for an embryo transfer and again, my doctor was examining my uterus and she mentioned that I have polyps in my uterus and when I referred to my past report just to see that what it said in 2024 i found about the hyperplasia and when I did some googling, I understood that this is a serious condition that should have been taken care. I am due for another hysteroscopy but I am scared as this was ignored. Reports from 2024 biopsy attached
Hello doctor my father is 75 yrs old.. from last 4 years he diagnosed with ckd but before 2 months his hb level very low. But now his condition is better but hb is 8 and platelets is 65000 his creatinine level is 5 . 15 and other 2 reports I attach.. so please tell me is my father have blood cancer?
My father is suffering from CLM (Chronic Myeloid Leukemia), Local Oncologist advised to take "BOSUTINIB 500 mg" but the Medicine doesn't suits on him, so many health issues arises after taking the Medicine. Earlier he was taking Tab "Imatinib 400" since 2018. Now patellate count has increased,& Hb is very low, Please Guide what to do now
