Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
I have checked everything except for colonoscopy, all are normal according to doctors, apart from grade 1 fatty liver, it is over 3 months I don't somke and drink, all CA markers are normal, still my fear of cancer keeps coming back, please suggest what to do
I have been having mild abdomen pain for about two months. Showed it to two different doctors, got an abdominal ultrasound done and they said everything's normal and gave medicine for gastric trouble.
However I'm really worried since I'm also getting occassional constipation and slightly flat stools at times though I did not notice any blood.
Should I just go to a proctologist and get it checked out?
My mother was diagnosed upfront as metastatic breast cancer on Nov 2023. At that time it was ER PR positive Her2 negative so first treatment was taxol chemo 6 cycle and then tumor reduction and given palbociclib tablet with letrozole for an year and half hr then further scan showed increased. So again biopsy done and it showed tnbc and also ngs panel done and it says pic3 mutation and now completed 6 cycles of carbo and docetaxol chemo and waiting fof pet scan now but doctor sayinf next treatment will be Alpelisib and Fulvesterant injection. But this alpelisib is too costly here in india and also not sure whether insurance is gonna cover it. Any advise? Attached ngs report
My father have been diagnosed with a small mass lesion in kidney less than 4 cm, exophytic, nephrometry score is 6, urologist suggested for partial nephrectomy, my fear is with the lung nodules as it can happen beacuse of metastasis, we have done PET CT , reporte are yet to come, the nodules are so small cannot be even takrn for biopsy, will do repeat CT after 6 months, but if cancer then what are the chances of recovery?
