Hello Doctor,
Seeking your opinion regarding a 71-year-old patient diagnosed with NSCLC favor squamous cell carcinoma (P40 diffuse positive, TTF1 negative) involving the right upper lobe. PET-CT shows a spiculated RUL lesion approx. 3.0 × 4.7 × 4.0 cm with SUV max 16.58. Mildly FDG-avid hilar/paratracheal nodes (SUV ~4.2) with some calcification noted. EBUS/TBNA from stations 4R, 7 and 11L showed no evidence of malignancy. Current staging documented as cT2bN1M0 (Stage IIB). Proposed plan is neoadjuvant chemotherapy followed by reassessment for surgery.
Would appreciate guidance on:
1. Whether chemo + surgery appears the optimal curative-intent approach in this case.
2. Whether adding immunotherapy to neoadjuvant chemotherapy would significantly improve outcomes.
3. Whether current imaging/EBUS findings sufficiently support N1 staging or need further nodal evaluation.
Thank you.
Hi, as part of my pre-IVF evaluation I underwent a hysteroscopy procedure in 2024. The biopsy results came back negative for CD138 but showed signs of endometrial hyperplasia. After this I was induced for egg retrieval twice back to back and then I took a break for a year. All this while I was never given any treatment for hyperplasia. Now this year that is 2026, I started my IVF journey again and my uterus had polyps. Since I am not a doctor, I do not understand why I was not given any treatment for hyperplasia. I only understood this when I did some study on my old report findings. I am now scared that what if it turned into cancer. My whole life would go for a toss for an ignorant doctor. What are you experience in such cases. What is the most worst that can happen to me. I will be doing a biopsy again but I want to know the reality what to expect.
I see now a days that many people after 60 years are diagnosed with cancer . The thing is, it is diagnosed in the last stage. Is there a test that we can perform every 6 months that can point out early stage cancer any where in the body?.
Hello doctor my father is 75 yrs old.. from last 4 years he diagnosed with ckd but before 2 months his hb level very low. But now his condition is better but hb is 8 and platelets is 65000 his creatinine level is 5 . 15 and other 2 reports I attach.. so please tell me is my father have blood cancer?
Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
