Malignant Melanoma Treatment

Health Q&A
Painless Groin Lymph Node Swelling

My grandmother is 72 years old and has painless external swelling/lumps near the groin/private-part area. She is otherwise normal, but she gets anxious and her BP increases during hospital visits. We consulted a gynecologist and general physician. Ultrasound report mentions bilateral inguinal nodal mass lesions and suprapubic lymph nodes, largest around 33 × 30 mm, with loss of fatty hilum and increased vascularity on Doppler. Impression says morphology is indeterminate/sonographically suspicious: lymphomatous / metastatic / granulomatous lymphadenitis. Report advised FNAC/core/excision biopsy and MRI pelvis with contrast. Please advise which specialist we should consult first: gynecologic oncologist, surgical oncologist, medical oncologist, or general surgeon? Also, should we proceed with FNAC/core biopsy first, or MRI pelvis with contrast first?

Advice for non small lung cancer - sqcc

Hello Doctor, Seeking your opinion regarding a 71-year-old patient diagnosed with NSCLC favor squamous cell carcinoma (P40 diffuse positive, TTF1 negative) involving the right upper lobe. PET-CT shows a spiculated RUL lesion approx. 3.0 × 4.7 × 4.0 cm with SUV max 16.58. Mildly FDG-avid hilar/paratracheal nodes (SUV ~4.2) with some calcification noted. EBUS/TBNA from stations 4R, 7 and 11L showed no evidence of malignancy. Current staging documented as cT2bN1M0 (Stage IIB). Proposed plan is neoadjuvant chemotherapy followed by reassessment for surgery. Would appreciate guidance on: 1. Whether chemo + surgery appears the optimal curative-intent approach in this case. 2. Whether adding immunotherapy to neoadjuvant chemotherapy would significantly improve outcomes. 3. Whether current imaging/EBUS findings sufficiently support N1 staging or need further nodal evaluation. Thank you.

Untreated endometrial hyperplasia

Hi, as part of my pre-IVF evaluation I underwent a hysteroscopy procedure in 2024. The biopsy results came back negative for CD138 but showed signs of endometrial hyperplasia. After this I was induced for egg retrieval twice back to back and then I took a break for a year. All this while I was never given any treatment for hyperplasia. Now this year that is 2026, I started my IVF journey again and my uterus had polyps. Since I am not a doctor, I do not understand why I was not given any treatment for hyperplasia. I only understood this when I did some study on my old report findings. I am now scared that what if it turned into cancer. My whole life would go for a toss for an ignorant doctor. What are you experience in such cases. What is the most worst that can happen to me. I will be doing a biopsy again but I want to know the reality what to expect.

Hair dye after cancer diagnosis

I am a 47 year old female was diagnosed with pT1c N0 M0 IDC grade 2 hormone positive her2 negative breast cancer In May 2025 (last year).. had lumpectomy, no chemo needed, had radiation and currently on tamoxifen..had my one year PET CT all clear...can I use hair dye?..keep reading that it causes cancer...any suggestions which hair dye can be used safely Thanks

Cancer screening

I see now a days that  many people after 60 years are diagnosed with cancer . The thing is, it is diagnosed in the last stage. Is there a test that we can perform every 6 months that can point out early stage cancer any where in the body?.

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Doctors
Dr. William  Hicks - Internal Medicine
Dr. William Hicks Internal Medicine (Medical School, Fellowship in Neurology - Vascular, Residency in Neurology, Internship, Transitional Year, Medical degree, DO, Internship) 52 years experience Ohio State Brain and Spine Hospital
Weinland Park, COLUMBUS
Dr. JAMES G SIVARD - General Surgeon
Dr. JAMES G SIVARD General Surgeon (Medical School, Internship, Residency) 47 years experience OhioHealth Doctors Hospital
Forest Park West, COLUMBUS
Dr. Timothy  Moore - Internal Medicine
Dr. Timothy Moore Internal Medicine (Residency, Medical School, B.S., Internship-Internal Medicine, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology) 45 years experience Select Specialty Hospital - Columbus
Short North, COLUMBUS
Dr. Jeffrey  Zangmeister - Internal Medicine
Dr. Jeffrey Zangmeister Internal Medicine (Fellowship, Residency, Medical School, Internship, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology, Medical Education, Fellowship 2, Residency - ID, Class of 1981) 45 years experience Zangmeister Cancer Center
Columbus 43222, COLUMBUS
Dr. Michael A. Caligiuri - Internal Medicine
Dr. Michael A. Caligiuri Internal Medicine (Medical School, Residency, Summa Cum Laude, Phi Beta Kappa, Master’s Degree in Physiology, Medical degree, DO, B.A., M.A., M.D., Undergraduate Degree in Humanities and Health Science) 43 years experience The James Cancer Center
Columbus 43210, COLUMBUS