Malignant Melanoma Treatment

Health Q&A
6.5 cm hamartoma in left breast

Hi my mother had her routine mammogram revealed 6.5 cm hamartoma in left breast without any symptoms. Is that dangerous, what is the treatment for that??

Seeking Treatment options for cancer

Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.

Fear of Cancer

I have checked everything except for colonoscopy, all are normal according to doctors, apart from grade 1 fatty liver, it is over 3 months I don't somke and drink, all CA markers are normal, still my fear of cancer keeps coming back, please suggest what to do

Adenocaricoma of stomach pylorus

Hi, My father underwent radical gastrectomy surgery for adenocaricoma of stomach. The hispathalogy report has come and stage is 2A , pT3N0 Need suggestions/views if the chemo can be delayed for 2 months as there is a important function amd father is not agreeing to take chemo before that fearing side efffects Attaching the report here.

Tnbc with pik3

Hi, My mother got diagnosed with upfront mbc on nov 2023 and that time it was er pr +ve and her2 negative so taxol given for 6 cycle then palbociclib with letro went for nearly 1.7 yrs then progression and did re biopsy then its changed to triple negative and also did gene and ngs test. Gene test came negative but ngs test showed pik3ca mutation and pd L1 also came negative. Then docetaxol and carboplaton chemo went for 6 cycle then few days back pet scan done but no response and its progressed again on liver. Now doctor suggested alpelisib and fulvestrant and started on it. Am really worried will alpelisib works on this tnbc? And how long can be managed and also aide effects etc.

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Substance Abuse & Cancer

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Doctors
Dr. William  Hicks - Internal Medicine
Dr. William Hicks Internal Medicine (Medical School, Fellowship in Neurology - Vascular, Residency in Neurology, Internship, Transitional Year, Medical degree, DO, Internship) 52 years experience Ohio State Brain and Spine Hospital
Weinland Park, COLUMBUS
Dr. JAMES G SIVARD - General Surgeon
Dr. JAMES G SIVARD General Surgeon (Medical School, Internship, Residency) 47 years experience OhioHealth Doctors Hospital
Forest Park West, COLUMBUS
Dr. Timothy  Moore - Internal Medicine
Dr. Timothy Moore Internal Medicine (Residency, Medical School, B.S., Internship-Internal Medicine, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology) 45 years experience Select Specialty Hospital - Columbus
Short North, COLUMBUS
Dr. Jeffrey  Zangmeister - Internal Medicine
Dr. Jeffrey Zangmeister Internal Medicine (Fellowship, Residency, Medical School, Internship, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology, Medical Education, Fellowship 2, Residency - ID, Class of 1981) 45 years experience Zangmeister Cancer Center
Columbus 43222, COLUMBUS
Dr. Michael A. Caligiuri - Internal Medicine
Dr. Michael A. Caligiuri Internal Medicine (Medical School, Residency, Summa Cum Laude, Phi Beta Kappa, Master’s Degree in Physiology, Medical degree, DO, B.A., M.A., M.D., Undergraduate Degree in Humanities and Health Science) 43 years experience The James Cancer Center
Columbus 43210, COLUMBUS