Chronic Myeloid Leukemia Treatment

Health Q&A
Rectosigmoid mass

My dad had bowel on and off for 6 months. A gastro specialist did colonoscopy and report said a mass in rectosigmoid region 10cm from anal bulge neoplastic? pet ct said luminal narrowing of the colon wall causing dilation of large bowel immedietly we  got the surgery done immedietly and tumour removed tumour biopsy said  all 12 lymph nodes are free t3N0 lvi plus pni plus emvi plus and high budding. Heart ef 40 to 45 percent. My question is that shall we go for ctdna or not and also as per mosiac trial they say that chemo specially oxilaplatin benefit in high risk stage 2 disease is very limited compared to stage 3 disease so shall we skip oxilaplatin and  prefer only s1  or skip chemo totally if ctdna negative Please advise whether to do ct dna or go for chemo directly or omit chemo totally outwieghing the risk of toxicity

All 12 nodes free, lvi, pni + colon

My dad was having stool on and off since last 6 months  after doing colonoscopy we noticed a mass in rectosigmoid region 10cm from anal bulge pet ct said luminal narrwing in rectosigmoid region causing dilation of proximal larhe bowel  he underwent colostomy surgery and is now recovering. doctors prescribed  chemo qfter it was mss and eF of heart 45 percent with oxilaplatin and s1. my question is that isnt oxilaplatin too toxic for high risk stage 2 because in mosiac trail they say that oxilaplatin almost adds neglible benefits in overall life for  high risk stage 2 patients compared to stage 3 patients...also he is very fine walking eating smiling and energetic well i m very confused that after chemo it might not be the same...pls help also is ctdna test or any other tests required to check further or chemo is important. we are giving him superb high antioxidant diet in his recovery days after surgery

Untreated endometrial hyperplasia

Hi, as part of my pre-IVF evaluation I underwent a hysteroscopy procedure in 2024. The biopsy results came back negative for CD138 but showed signs of endometrial hyperplasia. After this I was induced for egg retrieval twice back to back and then I took a break for a year. All this while I was never given any treatment for hyperplasia. Now this year that is 2026, I started my IVF journey again and my uterus had polyps. Since I am not a doctor, I do not understand why I was not given any treatment for hyperplasia. I only understood this when I did some study on my old report findings. I am now scared that what if it turned into cancer. My whole life would go for a toss for an ignorant doctor. What are you experience in such cases. What is the most worst that can happen to me. I will be doing a biopsy again but I want to know the reality what to expect.

Hair dye after cancer diagnosis

I am a 47 year old female was diagnosed with pT1c N0 M0 IDC grade 2 hormone positive her2 negative breast cancer In May 2025 (last year).. had lumpectomy, no chemo needed, had radiation and currently on tamoxifen..had my one year PET CT all clear...can I use hair dye?..keep reading that it causes cancer...any suggestions which hair dye can be used safely Thanks

Ckd patient

Hello doctor my father is 75 yrs old.. from last 4 years he diagnosed with ckd but before 2 months his hb level very low. But now his condition is better but hb is 8 and platelets is 65000 his creatinine level is 5 . 15 and other 2 reports I attach.. so please tell me is my father have blood cancer?

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Doctors
Dr. William  Hicks - Internal Medicine
Dr. William Hicks Internal Medicine (Medical School, Fellowship in Neurology - Vascular, Residency in Neurology, Internship, Transitional Year, Medical degree, DO, Internship) 52 years experience Ohio State Brain and Spine Hospital
Weinland Park, COLUMBUS
Dr. JAMES G SIVARD - General Surgeon
Dr. JAMES G SIVARD General Surgeon (Medical School, Internship, Residency) 47 years experience OhioHealth Doctors Hospital
Forest Park West, COLUMBUS
Dr. Timothy  Moore - Internal Medicine
Dr. Timothy Moore Internal Medicine (Residency, Medical School, B.S., Internship-Internal Medicine, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology) 45 years experience Select Specialty Hospital - Columbus
Short North, COLUMBUS
Dr. Jeffrey  Zangmeister - Internal Medicine
Dr. Jeffrey Zangmeister Internal Medicine (Fellowship, Residency, Medical School, Internship, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology, Medical Education, Fellowship 2, Residency - ID, Class of 1981) 45 years experience Zangmeister Cancer Center
Columbus 43222, COLUMBUS
Dr. Michael A. Caligiuri - Internal Medicine
Dr. Michael A. Caligiuri Internal Medicine (Medical School, Residency, Summa Cum Laude, Phi Beta Kappa, Master’s Degree in Physiology, Medical degree, DO, B.A., M.A., M.D., Undergraduate Degree in Humanities and Health Science) 43 years experience The James Cancer Center
Columbus 43210, COLUMBUS