Hi,
My mother got diagnosed with upfront mbc on nov 2023 and that time it was er pr +ve and her2 negative so taxol given for 6 cycle then palbociclib with letro went for nearly 1.7 yrs then progression and did re biopsy then its changed to triple negative and also did gene and ngs test. Gene test came negative but ngs test showed pik3ca mutation and pd L1 also came negative. Then docetaxol and carboplaton chemo went for 6 cycle then few days back pet scan done but no response and its progressed again on liver. Now doctor suggested alpelisib and fulvestrant and started on it. Am really worried will alpelisib works on this tnbc? And how long can be managed and also aide effects etc.
I have the cyst on the back of the neck in nape area where hair line ends atleast from 3 years . And suddenly from past 1year it grows a little it doesn't give any discomfort to me and it feels like movable it feels like 2 cm soft marble . Should I worry or not ?
Please find link below and suggest it's a tumor or not and what to do if it's exist https://jeeyo.actoneng.com:8082/view.html
My mother was diagnosed upfront as metastatic breast cancer on Nov 2023. At that time it was ER PR positive Her2 negative so first treatment was taxol chemo 6 cycle and then tumor reduction and given palbociclib tablet with letrozole for an year and half hr then further scan showed increased. So again biopsy done and it showed tnbc and also ngs panel done and it says pic3 mutation and now completed 6 cycles of carbo and docetaxol chemo and waiting fof pet scan now but doctor sayinf next treatment will be Alpelisib and Fulvesterant injection. But this alpelisib is too costly here in india and also not sure whether insurance is gonna cover it. Any advise? Attached ngs report
Need consultation with best uro Oncologist in New Delhi. BCG 80 mg applied 6 times at an interval of one week, after cystoscopy no appearance of tumor cells, but then after maintenance dose 3 times at an interval of one week, lesions appear, may be tumor.
