What should be the next treatment? How can we treat this Conventional prostatic adenocarcinoma with neuroendocrine differentiation and an extensive small cell type? He has aged alot , psa is 1.1, Intense FDG uptake noted in peripheral zone of right lobe of enlarged prostate (measures 5.0x4.3 cm);
SUVmax 10.9
FDG avid bilateral external iliac, left obturator nodes; ~ 3.1x2.5 cm, SUVmax 9.5
FDG avid few bilateral hilar, subcarinal, paratracheal, prevascular nodes (largest measures 1.8x0.9 cm;
SUVmax 8.5), few of them demonstrating hyperattenuation of NCCT thorax: favours the granulomatous etiology.
No other significant adenopathy noted
FDG avid extensive lytic and marrow lesions (few with associated soft tissue; Intraspinal extension at the level of few dorsal-lumbar vertebrae and sacrum) are noted involving axial and proximal appendicular skeleton; SUVmax 9.5.
Variable FDG avid varying sized hypodense lesions in both lobes of liver; largest measures ~ 2.5x3.0 cm (segment V), SUVmax 14.5
Hi,
My father underwent radical gastrectomy surgery for adenocaricoma of stomach.
The hispathalogy report has come and stage is 2A , pT3N0
Need suggestions/views if the chemo can be delayed for 2 months as there is a important function amd father is not agreeing to take chemo before that fearing side efffects
Attaching the report here.
Hi,
My mother got diagnosed with upfront mbc on nov 2023 and that time it was er pr +ve and her2 negative so taxol given for 6 cycle then palbociclib with letro went for nearly 1.7 yrs then progression and did re biopsy then its changed to triple negative and also did gene and ngs test. Gene test came negative but ngs test showed pik3ca mutation and pd L1 also came negative. Then docetaxol and carboplaton chemo went for 6 cycle then few days back pet scan done but no response and its progressed again on liver. Now doctor suggested alpelisib and fulvestrant and started on it. Am really worried will alpelisib works on this tnbc? And how long can be managed and also aide effects etc.
My mother was diagnosed upfront as metastatic breast cancer on Nov 2023. At that time it was ER PR positive Her2 negative so first treatment was taxol chemo 6 cycle and then tumor reduction and given palbociclib tablet with letrozole for an year and half hr then further scan showed increased. So again biopsy done and it showed tnbc and also ngs panel done and it says pic3 mutation and now completed 6 cycles of carbo and docetaxol chemo and waiting fof pet scan now but doctor sayinf next treatment will be Alpelisib and Fulvesterant injection. But this alpelisib is too costly here in india and also not sure whether insurance is gonna cover it. Any advise? Attached ngs report
I have white discharge from my right breast nipple, when I squeezed it, a small white drop came out. I have a slight pain in my nipple. Then my periods are delayed. Then I have hypothyroidism. What could be the reason? Is there a chance of cancer?
