Pancreas cancer Treatment

Health Q&A
Advanced stage lung adenocarcinoma

My mother is suffering from advanced(stage IV) Lung adenocarcinoma, she was diagnosed in December 2024 with metasis to liver and bones and she was further put on targeted therapy as it was EGFR and TP53 mutated- Osimertinib and Chemotherapy and it worked and resulted clear PET CT scans until recently . After a year of diagnosis, recently in May 2026 she went through PET CT scans following a swallowing difficulty and it was found that the cancer had become active again(not at the primary site) at the either side of the hilar nodes and in the esophagus (outer part not inside) now doctor has recommended Amivantamab and carboplatin chemotherapy. I want to know if this will work as she is havina a lot of complication while swallowing food and is having purely liquid diet. For how much time will it be effective? Doctor has said 1yr so really one yr or it depends? Is the line of treatment that is being followed ,correct ?

Prostate cancer or infection stage 4

Hello Doctor, my grandfather (Nanu) has Stage 4 prostate cancer and we are from Alwar, Rajasthan. He has severe pain from lower back/waist area to knees. Earlier, his testicles were surgically removed and currently he is on chemotherapy medicines. It has been 5 days since medicines started and he is gradually becoming weaker. Now he is finding it difficult to walk properly and we are very concerned. Could you please guide whether this is expected or urgent? Also, if needed, could you recommend a good specialist near "Jaipur", Delhi, or nearby areas? Could you please guide us regarding what kind of diet/food he should take during this time? Also, are there any foods we should avoid?

Rectosigmoid mass

My dad had bowel on and off for 6 months. A gastro specialist did colonoscopy and report said a mass in rectosigmoid region 10cm from anal bulge neoplastic? pet ct said luminal narrowing of the colon wall causing dilation of large bowel immedietly we  got the surgery done immedietly and tumour removed tumour biopsy said  all 12 lymph nodes are free t3N0 lvi plus pni plus emvi plus and high budding. Heart ef 40 to 45 percent. My question is that shall we go for ctdna or not and also as per mosiac trial they say that chemo specially oxilaplatin benefit in high risk stage 2 disease is very limited compared to stage 3 disease so shall we skip oxilaplatin and  prefer only s1  or skip chemo totally if ctdna negative Please advise whether to do ct dna or go for chemo directly or omit chemo totally outwieghing the risk of toxicity

Squamous cell carcinoma in neck right

My grand mother was diagnosed with neck cancer right side in march 25 treatment ongoing chemo pills taken and rt done in jan. Now she is unable to eat anything and weakness is there. Pipe is inserted. Reports attached. Need opinion

All 12 nodes free, lvi, pni + colon

My dad was having stool on and off since last 6 months  after doing colonoscopy we noticed a mass in rectosigmoid region 10cm from anal bulge pet ct said luminal narrwing in rectosigmoid region causing dilation of proximal larhe bowel  he underwent colostomy surgery and is now recovering. doctors prescribed  chemo qfter it was mss and eF of heart 45 percent with oxilaplatin and s1. my question is that isnt oxilaplatin too toxic for high risk stage 2 because in mosiac trail they say that oxilaplatin almost adds neglible benefits in overall life for  high risk stage 2 patients compared to stage 3 patients...also he is very fine walking eating smiling and energetic well i m very confused that after chemo it might not be the same...pls help also is ctdna test or any other tests required to check further or chemo is important. we are giving him superb high antioxidant diet in his recovery days after surgery

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Doctors
Dr. William  Hicks - Internal Medicine
Dr. William Hicks Internal Medicine (Medical School, Fellowship in Neurology - Vascular, Residency in Neurology, Internship, Transitional Year, Medical degree, DO, Internship) 52 years experience Ohio State Brain and Spine Hospital
Weinland Park, COLUMBUS
Dr. JAMES G SIVARD - General Surgeon
Dr. JAMES G SIVARD General Surgeon (Medical School, Internship, Residency) 47 years experience OhioHealth Doctors Hospital
Forest Park West, COLUMBUS
Dr. Timothy  Moore - Internal Medicine
Dr. Timothy Moore Internal Medicine (Residency, Medical School, B.S., Internship-Internal Medicine, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology) 45 years experience Select Specialty Hospital - Columbus
Short North, COLUMBUS
Dr. Jeffrey  Zangmeister - Internal Medicine
Dr. Jeffrey Zangmeister Internal Medicine (Fellowship, Residency, Medical School, Internship, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology, Medical Education, Fellowship 2, Residency - ID, Class of 1981) 45 years experience Zangmeister Cancer Center
Columbus 43222, COLUMBUS
Dr. Michael A. Caligiuri - Internal Medicine
Dr. Michael A. Caligiuri Internal Medicine (Medical School, Residency, Summa Cum Laude, Phi Beta Kappa, Master’s Degree in Physiology, Medical degree, DO, B.A., M.A., M.D., Undergraduate Degree in Humanities and Health Science) 43 years experience The James Cancer Center
Columbus 43210, COLUMBUS