I have been a CML patient since 2016 and have had undetectable reports since 2023. Since last year due to family and personal issues. I became alcohol sober and can't skip any day. I was told by a doctor friend that Neltrexone 50mg will help me to stop alcohol. But I am afraid whether it will interact with my CML medicine. Please advise I am living a very bad life.
Please help me answer.
Good evening Doctor.
I had intramucosal adenocarcinoma of the rectum about 9 years ago, arising from a tubulovillous adenoma (2 × 2 cm), moderately differentiated, with no invasion beyond the muscularis mucosa. Only polypectomy was done, and no further treatment was required. The report showed MSI negative / MMR proficient.
At that time MRI pelvis and CT scan were normal, and post-polypectomy site biopsy showed no dysplasia or malignancy.
Follow-up done regularly: • Colonoscopy – about 10 times, all normal (last on 12 November 2025)
• USG whole abdomen – 10 times, all normal
• Blood tests – about 6 times, normal
• Chest X-ray (PA) – 4 times, normal
Kindly advise the appropriate interval for future surveillance colonoscopy. Also, if a new polyp appears in future, would it necessarily be malignant in my case, or usually benign?
. Kindly send your advice by SMS when convenient. Thank you.
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