Health Q&A
Conventional prostatic adenocarcinoma

What should be the next treatment? How can we treat this Conventional prostatic adenocarcinoma with neuroendocrine differentiation and an extensive small cell type? He has aged alot , psa is 1.1, Intense FDG uptake noted in peripheral zone of right lobe of enlarged prostate (measures 5.0x4.3 cm); SUVmax 10.9 FDG avid bilateral external iliac, left obturator nodes; ~ 3.1x2.5 cm, SUVmax 9.5 FDG avid few bilateral hilar, subcarinal, paratracheal, prevascular nodes (largest measures 1.8x0.9 cm; SUVmax 8.5), few of them demonstrating hyperattenuation of NCCT thorax: favours the granulomatous etiology. No other significant adenopathy noted FDG avid extensive lytic and marrow lesions (few with associated soft tissue; Intraspinal extension at the level of few dorsal-lumbar vertebrae and sacrum) are noted involving axial and proximal appendicular skeleton; SUVmax 9.5. Variable FDG avid varying sized hypodense lesions in both lobes of liver; largest measures ~ 2.5x3.0 cm (segment V), SUVmax 14.5

Renal Mass and Lung Nodules

Recently did a PET SCAN for my father, where the Renal mass is less than 4 cm, FDG intake is low and for the lung nodules comments are looks like inflamatory than metastasis, we are planinng for Nephrectomy, but am worried with the lung nodules , can anyone please suggest

Intramucosal andenocarcinoma

Good evening Doctor. I had intramucosal adenocarcinoma of the rectum about 9 years ago, arising from a tubulovillous adenoma (2 × 2 cm), moderately differentiated, with no invasion beyond the muscularis mucosa. Only polypectomy was done, and no further treatment was required. The report showed MSI negative / MMR proficient. At that time MRI pelvis and CT scan were normal, and post-polypectomy site biopsy showed no dysplasia or malignancy. Follow-up done regularly: • Colonoscopy – about 10 times, all normal (last on 12 November 2025) • USG whole abdomen – 10 times, all normal • Blood tests – about 6 times, normal • Chest X-ray (PA) – 4 times, normal Kindly advise the appropriate interval for future surveillance colonoscopy. Also, if a new polyp appears in future, would it necessarily be malignant in my case, or usually benign? . Kindly send your advice by SMS when convenient. Thank you.

Small mass lesion in kidney,lung nodule

My father have been diagnosed with a small mass lesion in kidney less than 4 cm, exophytic, nephrometry score is 6, urologist suggested for partial nephrectomy, my fear is with the lung nodules as it can happen beacuse of metastasis, we have done PET CT , reporte are yet to come, the nodules are so small cannot be even takrn for biopsy, will do repeat CT after 6 months, but if cancer then what are the chances of recovery?

Cancer symptoms

I have white discharge from my right breast nipple, when I squeezed it, a small white drop came out. I have a slight pain in my nipple. Then my periods are delayed. Then I have hypothyroidism. What could be the reason? Is there a chance of cancer?

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Doctors
Dr. William  Hicks - Internal Medicine
Dr. William Hicks Internal Medicine (Medical School, Fellowship in Neurology - Vascular, Residency in Neurology, Internship, Transitional Year, Medical degree, DO, Internship) 52 years experience Ohio State Brain and Spine Hospital
Weinland Park, COLUMBUS
Dr. JAMES G SIVARD - General Surgeon
Dr. JAMES G SIVARD General Surgeon (Medical School, Internship, Residency) 47 years experience OhioHealth Doctors Hospital
Forest Park West, COLUMBUS
Dr. Timothy  Moore - Internal Medicine
Dr. Timothy Moore Internal Medicine (Residency, Medical School, B.S., Internship-Internal Medicine, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology) 45 years experience Select Specialty Hospital - Columbus
Short North, COLUMBUS
Dr. Jeffrey  Zangmeister - Internal Medicine
Dr. Jeffrey Zangmeister Internal Medicine (Fellowship, Residency, Medical School, Internship, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology, Medical Education, Fellowship 2, Residency - ID, Class of 1981) 45 years experience Zangmeister Cancer Center
Columbus 43222, COLUMBUS
Dr. Michael A. Caligiuri - Internal Medicine
Dr. Michael A. Caligiuri Internal Medicine (Medical School, Residency, Summa Cum Laude, Phi Beta Kappa, Master’s Degree in Physiology, Medical degree, DO, B.A., M.A., M.D., Undergraduate Degree in Humanities and Health Science) 43 years experience The James Cancer Center
Columbus 43210, COLUMBUS