Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
My mother in-law underwent a biopsy test and it revealed the presence of the disease. We were told the disease is in its early stages. Please refer the attached report and confirm.
Hi,
My mother got diagnosed with upfront mbc on nov 2023 and that time it was er pr +ve and her2 negative so taxol given for 6 cycle then palbociclib with letro went for nearly 1.7 yrs then progression and did re biopsy then its changed to triple negative and also did gene and ngs test. Gene test came negative but ngs test showed pik3ca mutation and pd L1 also came negative. Then docetaxol and carboplaton chemo went for 6 cycle then few days back pet scan done but no response and its progressed again on liver. Now doctor suggested alpelisib and fulvestrant and started on it. Am really worried will alpelisib works on this tnbc? And how long can be managed and also aide effects etc.
My father have been diagnosed with a small mass lesion in kidney less than 4 cm, exophytic, nephrometry score is 6, urologist suggested for partial nephrectomy, my fear is with the lung nodules as it can happen beacuse of metastasis, we have done PET CT , reporte are yet to come, the nodules are so small cannot be even takrn for biopsy, will do repeat CT after 6 months, but if cancer then what are the chances of recovery?
I have white discharge from my right breast nipple, when I squeezed it, a small white drop came out. I have a slight pain in my nipple. Then my periods are delayed. Then I have hypothyroidism. What could be the reason? Is there a chance of cancer?
