Polycythemia Vera Treatment

Health Q&A
Rectosigmoid mass

My dad had bowel on and off for 6 months. A gastro specialist did colonoscopy and report said a mass in rectosigmoid region 10cm from anal bulge neoplastic? pet ct said luminal narrowing of the colon wall causing dilation of large bowel immedietly we  got the surgery done immedietly and tumour removed tumour biopsy said  all 12 lymph nodes are free t3N0 lvi plus pni plus emvi plus and high budding. Heart ef 40 to 45 percent. My question is that shall we go for ctdna or not and also as per mosiac trial they say that chemo specially oxilaplatin benefit in high risk stage 2 disease is very limited compared to stage 3 disease so shall we skip oxilaplatin and  prefer only s1  or skip chemo totally if ctdna negative Please advise whether to do ct dna or go for chemo directly or omit chemo totally outwieghing the risk of toxicity

All 12 nodes free, lvi, pni + colon

My dad was having stool on and off since last 6 months  after doing colonoscopy we noticed a mass in rectosigmoid region 10cm from anal bulge pet ct said luminal narrwing in rectosigmoid region causing dilation of proximal larhe bowel  he underwent colostomy surgery and is now recovering. doctors prescribed  chemo qfter it was mss and eF of heart 45 percent with oxilaplatin and s1. my question is that isnt oxilaplatin too toxic for high risk stage 2 because in mosiac trail they say that oxilaplatin almost adds neglible benefits in overall life for  high risk stage 2 patients compared to stage 3 patients...also he is very fine walking eating smiling and energetic well i m very confused that after chemo it might not be the same...pls help also is ctdna test or any other tests required to check further or chemo is important. we are giving him superb high antioxidant diet in his recovery days after surgery

Ldh report high neutrophils

Wbc count anything from.12000 to 18000 always once reach 22000 also ldh report is normal as attached so why wbc is high Chronic prostatis leads to high WBC?

HIPEC treatment for Ovarian Cancer

Hello Doctor, my mother has ovarian cancer and has completed 4 cycles of neoadjuvant chemotherapy with very good response (CA-125 reduced from 273 to 11). Her treating team is now planning interval cytoreductive surgery with HIPEC. We would like to take an expert opinion specifically regarding whether HIPEC is truly necessary/beneficial in her case, considering the additional recovery burden and cost. Could you please help us in deciding if HIPEC would be necessary and effective ? Thank you.

Cancer screening

I see now a days that  many people after 60 years are diagnosed with cancer . The thing is, it is diagnosed in the last stage. Is there a test that we can perform every 6 months that can point out early stage cancer any where in the body?.

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Dr. William  Hicks - Internal Medicine
Dr. William Hicks Internal Medicine (Medical School, Fellowship in Neurology - Vascular, Residency in Neurology, Internship, Transitional Year, Medical degree, DO, Internship) 52 years experience Ohio State Brain and Spine Hospital
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Dr. Timothy  Moore - Internal Medicine
Dr. Timothy Moore Internal Medicine (Residency, Medical School, B.S., Internship-Internal Medicine, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology) 45 years experience Select Specialty Hospital - Columbus
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Dr. Jeffrey  Zangmeister - Internal Medicine
Dr. Jeffrey Zangmeister Internal Medicine (Fellowship, Residency, Medical School, Internship, Residency in Internal Medicine, Clinical Fellowship in Hematology and Medical Oncology, Medical Education, Fellowship 2, Residency - ID, Class of 1981) 45 years experience Zangmeister Cancer Center
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Dr. Michael A. Caligiuri - Internal Medicine
Dr. Michael A. Caligiuri Internal Medicine (Medical School, Residency, Summa Cum Laude, Phi Beta Kappa, Master’s Degree in Physiology, Medical degree, DO, B.A., M.A., M.D., Undergraduate Degree in Humanities and Health Science) 43 years experience The James Cancer Center
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