Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
My mother in-law underwent a biopsy test and it revealed the presence of the disease. We were told the disease is in its early stages. Please refer the attached report and confirm.
I have been having mild abdomen pain for about two months. Showed it to two different doctors, got an abdominal ultrasound done and they said everything's normal and gave medicine for gastric trouble.
However I'm really worried since I'm also getting occassional constipation and slightly flat stools at times though I did not notice any blood.
Should I just go to a proctologist and get it checked out?
Good evening Doctor.
I had intramucosal adenocarcinoma of the rectum about 9 years ago, arising from a tubulovillous adenoma (2 × 2 cm), moderately differentiated, with no invasion beyond the muscularis mucosa. Only polypectomy was done, and no further treatment was required. The report showed MSI negative / MMR proficient.
At that time MRI pelvis and CT scan were normal, and post-polypectomy site biopsy showed no dysplasia or malignancy.
Follow-up done regularly: • Colonoscopy – about 10 times, all normal (last on 12 November 2025)
• USG whole abdomen – 10 times, all normal
• Blood tests – about 6 times, normal
• Chest X-ray (PA) – 4 times, normal
Kindly advise the appropriate interval for future surveillance colonoscopy. Also, if a new polyp appears in future, would it necessarily be malignant in my case, or usually benign?
. Kindly send your advice by SMS when convenient. Thank you.
Hello my father has been diagnosed by HCC liver cancer BCLC stage Child pugh-A
Can u please suggest me treatment
Which is the best option immunotherapy Injections or TACE