Hello Doctor,
Seeking your opinion regarding a 71-year-old patient diagnosed with NSCLC favor squamous cell carcinoma (P40 diffuse positive, TTF1 negative) involving the right upper lobe. PET-CT shows a spiculated RUL lesion approx. 3.0 × 4.7 × 4.0 cm with SUV max 16.58. Mildly FDG-avid hilar/paratracheal nodes (SUV ~4.2) with some calcification noted. EBUS/TBNA from stations 4R, 7 and 11L showed no evidence of malignancy. Current staging documented as cT2bN1M0 (Stage IIB). Proposed plan is neoadjuvant chemotherapy followed by reassessment for surgery.
Would appreciate guidance on:
1. Whether chemo + surgery appears the optimal curative-intent approach in this case.
2. Whether adding immunotherapy to neoadjuvant chemotherapy would significantly improve outcomes.
3. Whether current imaging/EBUS findings sufficiently support N1 staging or need further nodal evaluation.
Thank you.
Plz anyone guide me about that. What to do...
Whether to go for chemo or else. And what is the outcome after chemo
Hi, as part of my pre-IVF evaluation I underwent a hysteroscopy procedure in 2024. The biopsy results came back negative for CD138 but showed signs of endometrial hyperplasia. After this I was induced for egg retrieval twice back to back and then I took a break for a year. All this while I was never given any treatment for hyperplasia. Now this year that is 2026, I started my IVF journey again and my uterus had polyps. Since I am not a doctor, I do not understand why I was not given any treatment for hyperplasia. I only understood this when I did some study on my old report findings. I am now scared that what if it turned into cancer. My whole life would go for a toss for an ignorant doctor. What are you experience in such cases. What is the most worst that can happen to me. I will be doing a biopsy again but I want to know the reality what to expect.
I am a 47 year old female was diagnosed with pT1c N0 M0 IDC grade 2 hormone positive her2 negative breast cancer In May 2025 (last year).. had lumpectomy, no chemo needed, had radiation and currently on tamoxifen..had my one year PET CT all clear...can I use hair dye?..keep reading that it causes cancer...any suggestions which hair dye can be used safely
Thanks
My father is suffering from CLM (Chronic Myeloid Leukemia), Local Oncologist advised to take "BOSUTINIB 500 mg" but the Medicine doesn't suits on him, so many health issues arises after taking the Medicine. Earlier he was taking Tab "Imatinib 400" since 2018. Now patellate count has increased,& Hb is very low, Please Guide what to do now
