Menkes Disease Treatment

Health Q&A
Left leg and Left arm unresponsive

I woke up with my left arm and left leg being heavier than my right for atleast 5 mins at 3am in the morning. Its been 5 days since. I could move my limbs but they were extremely stone heavy than right. No tingling or numbness just heavy. I was horrified. I have had a Brain MRI 3 years ago due to anxiety symptoms. It was normal back then. I have had strange symptoms like palm sized pressure in the left side top of my head which happened atleast 7 times last year and then completely stopped. The last pressure episode happened at nov 2025 when I woke up in the morning and suddenly had palm size pressure in the same area with my left index finger and left thumb tingling. It never happened since. However 5 days I had my left leg and arm feeling like it was being pulled stronger by gravity when I woke up randomly at 3am. I am only 22. I have been taking bisoprolol 2.5mg for 3 years due to severe anxiety. That medicine keeps my bp at 104/73, HR at 73 on rest. So far, it's always after sleep.

B12 B9 deficiency - Neurological symptom

Hi My serum value B12 226 pg/ml, past 1 year ago had 162 pg/ ml so doctor prescribed 3 re-nerve plus injection. My current MMA - 481, active b12- 32, Homocysteine >50, folate - 1.19, ferritin serum 32.3. I have been facing floating sensation for past 2 years reduction in libido, pins and needles pain in palms and feet and some time severe pins and needle pain in penis after ejaculation Already visited many doctors don't know which doctor to visit. My symptoms are not getting improved come and goes not able to judge what is happening Kindly suggest first course of treatment should it be b12 injection or some other treatment like oral supplements and also which doctor I have to visit?

Nerve weakness

I got a uti 6-7 before during treatment my sugar level where high don't know why after that I have many problem urinary bladder problems nerve weakness and many more i consult my urologist but it don't cure could it be a nerve problem

Restrictive movements

I had a accident, fall from motorcycle at around 30-40 km/ hr on 24 th May 2026 Had some cuts at knee and feeling of chest muscles tightness/heaviness Couldn’t walk for 2 weeks out of home Then Visited a orthopaedic He gave a medicine etodolac + thiocolchicoside Initial few days were good, but one day suddenly had a panic attack like wanting to throw kicks and hands in the air etc Stopped tooking those medication Now the pain in the muscles and knee has all gone , No problem in walking, etc Clear X rays of chest and knee But mind feels restrictive or hesitant while going out Like the actions I used to perform before bed rest feels very heavy or sluggish on the mind etc.

Spinal problem

Osteophytes and mild disc dessication. Perineural cysts in proximal sacral spinal canal at the level of $2 vertebra. Mild facet joint arthropathy at l5-$1 level. Subtle posterocentral disc protrusion at L4-L5 and L5-$1 levels causing mild anterior thecal sac indentation however there is no obvious impingement of nerve roots. AP spinal canal (thecal sac) diameter: L1-L2- 13.4mm L2-L3-11.8mm L3-L4 -11.5mm L4-L5-10.5mm L5-S1-10mm Spondylotic degenerative changes in form of loss of cervical lordosis, multilevel small marginal endplate osteophytes and disc dessication. Posterior disc osteophytic complexes from C3-C4 to C6-C7 levels causing mild anterior thecal sac indentation and mild narrowing of spinal canal. Few small perineural cysts are seen in bilateral neural foramina at multiple levels. At C4-C5 & C5-C6 levels, there is mild narrowing of right neural foramen with possible mild impingement of exiting nerve root.

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Doctors
Dr. Colleen M Opremcak - Neurologist
Dr. Colleen M Opremcak Neurologist (Chief Residency in Psychiatry, Class of 1982, Medical School, Residency - ID) 44 years experience Ohiohealth Behavioral Health
Columbus 43214, COLUMBUS
Dr. Michael Karl Racke - Neurologist
Dr. Michael Karl Racke Neurologist (Medical School, Class of 1985, Internship, Residency - ID, Fellowship 2, Medical degree, DO, Residency in Neurology, Fellowship in Neuroimmunology/Multiple Sclerosis, Internship-Internal Medicine) 41 years experience Hudson Regional Hospital
Columbus 43210, COLUMBUS
Dr. Daniel Jones - Neurologist
Dr. Daniel Jones Neurologist (Internship, Residency - ID, Neurology, Medical degree, DO, Fellowship 2, Class of 1989) 36 years experience Nationwide Children's Hospital
Canal Winchester, COLUMBUS
Dr. Punit Agrawal - Neurologist
Dr. Punit Agrawal Neurologist (Doctor of Osteopathic Medicine (DO), Medical School, Residency in Neurology, Internship-Internal Medicine, Medical Education, Class of 2020) 24 years experience Ohio State Outpatient Care New Albany
Westerville, COLUMBUS
Dr. Jason Lee Barfield - Neurologist
Dr. Jason Lee Barfield Neurologist (Medical degree, DO, Internship, Residency - ID, Fellowship 2, Residency in Neurology, Fellowship in Clinical Neurophysiology, Medical School) 24 years experience Ohiohealth Physician Group Neurology New Albany
Columbus 43230, COLUMBUS