Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
What should be the next treatment? How can we treat this Conventional prostatic adenocarcinoma with neuroendocrine differentiation and an extensive small cell type? He has aged alot , psa is 1.1, Intense FDG uptake noted in peripheral zone of right lobe of enlarged prostate (measures 5.0x4.3 cm);
SUVmax 10.9
FDG avid bilateral external iliac, left obturator nodes; ~ 3.1x2.5 cm, SUVmax 9.5
FDG avid few bilateral hilar, subcarinal, paratracheal, prevascular nodes (largest measures 1.8x0.9 cm;
SUVmax 8.5), few of them demonstrating hyperattenuation of NCCT thorax: favours the granulomatous etiology.
No other significant adenopathy noted
FDG avid extensive lytic and marrow lesions (few with associated soft tissue; Intraspinal extension at the level of few dorsal-lumbar vertebrae and sacrum) are noted involving axial and proximal appendicular skeleton; SUVmax 9.5.
Variable FDG avid varying sized hypodense lesions in both lobes of liver; largest measures ~ 2.5x3.0 cm (segment V), SUVmax 14.5
I have checked everything except for colonoscopy, all are normal according to doctors, apart from grade 1 fatty liver, it is over 3 months I don't somke and drink, all CA markers are normal, still my fear of cancer keeps coming back, please suggest what to do
Hi,
My father underwent radical gastrectomy surgery for adenocaricoma of stomach.
The hispathalogy report has come and stage is 2A , pT3N0
Need suggestions/views if the chemo can be delayed for 2 months as there is a important function amd father is not agreeing to take chemo before that fearing side efffects
Attaching the report here.
A teenager girl, having pain in the left side of my chest near heart for the past 4 months , got heart tests like Echo , ECG done , but the pain is still there with me , Sometimes blood , mucus comes in stool ( once a fortnight not very often) , weight fluctuates even after eating same foods, extreme tiredness, fatigue , and till now two times my ankles have swollen, nose bleed a little only once today..
Cardiac reports don't indicate any flaw , but I feel like my symptoms are with leukemia, by the way , I have my appointment with a grd doctor ( gastroenterologist) because parents are suggesting instead of any serious disease all this is included in grd disease, want to know what I can do.. please reply doctors..
