Hello Doctor,
Seeking your opinion regarding a 71-year-old patient diagnosed with NSCLC favor squamous cell carcinoma (P40 diffuse positive, TTF1 negative) involving the right upper lobe. PET-CT shows a spiculated RUL lesion approx. 3.0 × 4.7 × 4.0 cm with SUV max 16.58. Mildly FDG-avid hilar/paratracheal nodes (SUV ~4.2) with some calcification noted. EBUS/TBNA from stations 4R, 7 and 11L showed no evidence of malignancy. Current staging documented as cT2bN1M0 (Stage IIB). Proposed plan is neoadjuvant chemotherapy followed by reassessment for surgery.
Would appreciate guidance on:
1. Whether chemo + surgery appears the optimal curative-intent approach in this case.
2. Whether adding immunotherapy to neoadjuvant chemotherapy would significantly improve outcomes.
3. Whether current imaging/EBUS findings sufficiently support N1 staging or need further nodal evaluation.
Thank you.
I was undergoing IVF treatment which started in 2024 as part of my pre-IVF assessment. I was given a diagnostics hysteroscopy that revealed that I had hyperplasia without atypia in 2024. I don't remember that my doctor was concerned during that time and the only treatment that I was given was Crina 10 for 10 days for my spotting in leutal phase. Now I this year. I am due for an embryo transfer and again, my doctor was examining my uterus and she mentioned that I have polyps in my uterus and when I referred to my past report just to see that what it said in 2024 i found about the hyperplasia and when I did some googling, I understood that this is a serious condition that should have been taken care. I am due for another hysteroscopy but I am scared as this was ignored. Reports from 2024 biopsy attached
I see now a days that many people after 60 years are diagnosed with cancer . The thing is, it is diagnosed in the last stage. Is there a test that we can perform every 6 months that can point out early stage cancer any where in the body?.
My mother right breast 3 cm lump and biopsy report invasive carnicoma can you tell me please what Is the treatment
Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
