Pseudohypoparathyroidism Treatment

Health Q&A
Prediabetes

Can Istamet 50/500 dose be increased in prediabetes? Hba1c has risen from 6.3 to 6.4 in past 1 year. FBS mostly remains high normal 100-110. PPBS remain 130-140. Weight is 52.4 kg, 72 yrs Can I take Istamet 50/500 (sitagliptin/metformin) two tabs once a day if I m not diabetic but have Prediabetes? Is it safe to take  in early liver cirrhosis with no symptoms?

Cold and cough stomach upset from tomorr

Taking Amaryl 2mg twice daily and teneligliptin 20mg once. Average blood sugar is 155 and hb1c is 6.8 last month

HOMA-IR 6.4 at 29 — metformin needed?

29M, 98kg, 178cm (BMI 31). Fasting labs 22/06/2026. Fasting Glucose: 93 (normal) HbA1c: 5.7% (borderline) Fasting Insulin: 54 mIU/L (high, ref 2.6-24.9) HOMA-IR: 6.4 (high, ref 0.7-2.0) ALT 64, GGT 98 ( fatty liver), Vit D 16 (deficient). Hypertension on Cilnidipine. No diabetes. Endocrinologist advised only weight loss and vitamin D. But my HOMA-IR is 3x the upper limit. Should I be on metformin at this stage to address insulin resistance and protect against diabetes, or is weight loss alone the right approach? Also open to GLP-1 if appropriate given BMI 31.

Thyroid medication

My thyroid levels are under control at 2.589 (TSH) But my doctor suggested that I take Thyronorm 50 mcg daily. I have been doing that for four years now. I take the tablet at 8 am on empty stomach. It is a bit inconvenient for me. Can I take it in the evening say at 5 pm daily. I eat dinner at around 9.30 pm. In between, I drink juice during badminton at 8 pm and eat a small bite of brownie at 7.45 pm. Please advise if it is ok to take the tablet at 5 pm. Thanks.

Prediabetic condition

I am 40Y old . My father 75 has diabetes . In may month my hb1ac was 6, fasting sugar 93, fructosamine -215 ( lab test)pp was 130 .yesterday I ate white rice dal and potataies at 7 pm . It was full plate .My pp came out to be 174. First time my pp is like this . Next day fasting was 104. both pp and fasting on glucometerHave I progressed to diabetes within 2 months . I was eating one full mango everyday after dinner may be it can be the cause but my 174 reading was without mango( i didnt eat mango that day ). I am going for walk after dinner since in nuclear family and having toddler plue 8 to 5 job it is difficult to maintain much diet. I am too much stressed. Kindly guide me. I know i have to be careful but sudden high numbers are stressing me .

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Doctors
Dr. Joshua J. Joseph - Internal Medicine
Dr. Joshua J. Joseph Internal Medicine (Medical degree, DO, Internship, Residency - ID, Fellowship 2, Fellowship in Clinical Research Fellowship, Fellowship in Diabetes Research) 20 years experience Nationwide Children's Hospital
10 recommendations Canal Winchester, COLUMBUS
Dr. John D Blackman - Internal Medicine
Dr. John D Blackman Internal Medicine (Fellowship, Residency, Medical School, Residency - ID, Fellowship 2) 42 years experience OhioHealth Endocrinology Physicians
Columbus 43213, COLUMBUS
Dr. Elena A Christofides - Internal Medicine
Dr. Elena A Christofides Internal Medicine (Medical School, B.S., Residency - ID, Fellowship 2) 31 years experience MediZen Institute - Columbus Short North
Short North, COLUMBUS
Dr. Rundsarah Majed Tahboub - Internal Medicine
Dr. Rundsarah Majed Tahboub Internal Medicine (Residency, Medical School, Medical degree, DO, Fellowship in Endocrinology, Diabetes, and Metabolism, Residency in Internal Medicine, Medical Residency in Family Medicine, Fellowship in Endocrinology and Metabolism, Family Practice Residency) 28 years experience Millhon Clinic
Flint, COLUMBUS
Dr. Angela R Caffaratti - Family Physician
Dr. Angela R Caffaratti Family Physician (Residency, Medical School, Residency - ID) 28 years experience Ohio State Richard M. Ross Heart Hospital
Weinland Park, COLUMBUS