Type 2 Diabetes Treatment

Health Q&A
Prediabetes

Can Istamet 50/500 dose be increased in prediabetes? Hba1c has risen from 6.3 to 6.4 in past 1 year. FBS mostly remains high normal 100-110. PPBS remain 130-140. Weight is 52.4 kg, 72 yrs Can I take Istamet 50/500 (sitagliptin/metformin) two tabs once a day if I m not diabetic but have Prediabetes? Is it safe to take  in early liver cirrhosis with no symptoms?

HOMA-IR 6.4 at 29 — metformin needed?

29M, 98kg, 178cm (BMI 31). Fasting labs 22/06/2026. Fasting Glucose: 93 (normal) HbA1c: 5.7% (borderline) Fasting Insulin: 54 mIU/L (high, ref 2.6-24.9) HOMA-IR: 6.4 (high, ref 0.7-2.0) ALT 64, GGT 98 ( fatty liver), Vit D 16 (deficient). Hypertension on Cilnidipine. No diabetes. Endocrinologist advised only weight loss and vitamin D. But my HOMA-IR is 3x the upper limit. Should I be on metformin at this stage to address insulin resistance and protect against diabetes, or is weight loss alone the right approach? Also open to GLP-1 if appropriate given BMI 31.

Fasting Sugar Low, Hba1c 5.7

My fasting glucose was 70 mg/dL, but HbA1c was 5.7%. After 3–4 months of intermittent fasting/OMAD, HbA1c was still 5.8%. I was on mirtazapine 60 mg. My CBC showed Hb 14.9, RBC 5.89 million, MCV 76.4, MCH 25.3, RDW 16. Iron studies: serum iron 93 µg/dL, TIBC 305 µg/dL, transferrin saturation 30.5%, ferritin 88 ng/mL. Could this HbA1c be falsely elevated due to possible thalassemia trait or other RBC factors, or does this suggest true prediabetes despite a fasting glucose of 70?

My FBS is Greater Than PPs

Dear Sir, My Fasting Blood sugar 97 and My post pandrial sugar 83, and my Recent HBA1c : 5.4 Why is my FPS Is Greater Than PP (from  almost 20 days ). Is this Any problem ?? How can I overcome this? Sometimes I'm feeling tired. Pls Help

Extreme health anxiety

I was getting throat infections often, so I went and saw an ENT specialist. He immediately asked me to do a CT scan for sinus - PNS CT scan. He gave medicines too. The next day I went to the scan center, there were many warning signs. Even the nurse said it has radiation. Even ChatGPT said CT scan has radiation and shouldn't be done unnecessarily. I should have said, I will think about it and come tomorrow. But I paid the money then they asked to sign a paper that they are not responsible for any side effects. Then the report came back and the doctor said no sinus problem. But I feel extremely anxious about the side effects. I read so many articles online and they said even one CT scan can increase the cancer risk in future especially in women who are younger. I am around 25 years old, female. I asked the doctor and he gave me an anti-depressant but I am still not convinced. I am still feeling extremely lost. I feel like I spoiled my future. Please someone help me from this mental pain

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Doctors
Dr. Joshua J. Joseph - Internal Medicine
Dr. Joshua J. Joseph Internal Medicine (Medical degree, DO, Internship, Residency - ID, Fellowship 2, Fellowship in Clinical Research Fellowship, Fellowship in Diabetes Research) 20 years experience Nationwide Children's Hospital
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Dr. John D Blackman Internal Medicine (Fellowship, Residency, Medical School, Residency - ID, Fellowship 2) 42 years experience OhioHealth Endocrinology Physicians
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Dr. Rundsarah Majed Tahboub - Internal Medicine
Dr. Rundsarah Majed Tahboub Internal Medicine (Residency, Medical School, Medical degree, DO, Fellowship in Endocrinology, Diabetes, and Metabolism, Residency in Internal Medicine, Medical Residency in Family Medicine, Fellowship in Endocrinology and Metabolism, Family Practice Residency) 28 years experience Millhon Clinic
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Dr. Angela R Caffaratti - Family Physician
Dr. Angela R Caffaratti Family Physician (Residency, Medical School, Residency - ID) 28 years experience Ohio State Richard M. Ross Heart Hospital
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