Azoospermia (No Sperms in the Semen) does not always mean Donor Sperms.

This couple had been trying for pregnancy for ten long years. Wife's age is 29 years and all of her reports were normal. 

Husband's age is 35 years. Repeated Semen Analysis showed absent Sperms in the Semen. After physical examination (of Testicular Size) and investigations (blood for FSH, Testosterone), it was confirmed as a case of NOA (Non Obstructive Azoospermia)- no obstruction in Sperm Conducting Duct but there was problem in Sperm Production inside the testicles. 

We discussed 2 options - 

1) Intrauterine Insemination (IUI) using Donor Sperms. This is cheaper but success rate is low. They did not accept donor sperms.

2) ICSI (Intracytoplasmic Sperm Injection), which is a special form of IVF (In Vitro Fertilization), after attempting to collect his own sperms from his testicles by TESA (Testicular Sperm Aspiration). They initially hesitated to accept it because of the cost but finally agreed. 

The process of IVF started. The woman responded well to the ovarian stimulation. Good number of eggs were collected from her. TESA was done on the same day. ICSI was done. 

But the woman's uterus was not looking good to accept the embryos. So all the embryos were frozen. She was given 3 injections at monthly basis to decrease the size of her uterus and then embryo transfer was done.