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Persistent high eosinophils
My father, 63 male, has Type 2 Diabetes, Hypertension and CAD. He works with sheep (animal exposure) Had leg cellulitis in Aug 2025 (now settled). He is otherwise keeping well.
Eosinophils were already high in 2019 & 2022 (not investigated then). Recent reports again show marked eosinophilia (AEC earlier 4.96, later ~3.13; up to 35%). IgE is very high (~2650). No known allergies.
Other findings: Mild anemia (Hb 11.6), clear iron deficiency (Ferritin 18.8, saturation 6%), B12 normal, Coombs negative.
Seen by Haematology and Immunology. Doctor called it an “incidental finding” as he has been keeping well. Advised USG and possible genetic tests later.
Questions:
1. What are the most likely causes (long-standing high eos + high IgE + sheep exposure)?
2. Since he has been well for years, do we need to investigate urgently/promptly or can we take it slowly step by step?
3. Which tests should we prioritise now?
4. Any risk of silent organ damage even if he feels fine?
Thank you.
Answers (10)
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Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Need evaluation
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Need proper evaluation please consult for assessment and treatment
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Persistent eosinophilia in this range needs structured evaluation even if he feels well. I would repeat CBC with absolute eosinophil count and review the trend, then do stool ova/parasite testing (guided by exposure) and a careful medication review. Allergy/parasitic causes are common, but drug-related and clonal blood disorders must also be excluded. Depending on symptoms and examination, chest X-ray (or CT if indicated) and review with a haematologist/immunologist are appropriate, because silent organ involvement can occur. Please arrange a report review rather than ignoring this; you can book a Practo consult or visit me at Synergy Multispeciality Hospital, Miraj.
Next Steps
Repeat CBC/AEC trend, stool ova/parasite tests, medication review and examination first; add chest imaging and specialist review as indicated. Please share the reports through a Practo consult or visit me at Synergy Multispeciality Hospital, Miraj.
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If you would like to discuss your concern in more detail, please feel free to contact me on WhatsApp at nine one one nine two five five six nine nine. Alternatively, you can connect with me through the Practo app for a detailed consultation
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kindly do connect and consult with me for better treatment plan and advice on your case via PRACTO app
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Dr. Rohan Gumber
General Physician
1 yrs exp
Sri Ganganagar
If you would like to discuss your concern in more detail, please feel free to contact me on WhatsApp at eight six one nine six six nine nine zero six. Alternatively, you can connect with me through the Practo app for a detailed consultation
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Dr. Reesha Varshney
General Physician
1 yrs exp
Bareilly
Is there any history of recurrent respiratory illness??
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Dr. Vetsa Sri Krishna Chaitanya
General Physician
7 yrs exp
Rajahmundry
Need a few more details please consult for further evaluation and treatment
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Dr. Gaurav Jaiswal
General Physician
7 yrs exp
Jhansi
Avoid fried and spicy food
Water intake more
Green leafy vegetables more
Fiber meal
Walk
Do connect and consult
Will help you
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.