What is Triple Screen Test?

The triple screen test is a maternal blood screening test that looks for three specific substances: 

  1. AFP, 
  2. hCG, 
  3. Estriol. 

Is there any risk of Triple Screen Test?


It is a non-invasive procedure done through a blood test with no known risk to the mother or developing baby. 

How is the triple screen test performed?

The triple screen test involves drawing blood from the mother. 

The blood sample is then sent to the laboratory for testing. 

The results usually take a few days to receive. 

When is the triple screen test performed?

Between the 15th and 20th week of pregnancy 

Results obtained in the 16th -18 th week are said to be the most accurate. 

All pregnant women should be offered the triple screen, 

but it is recommended for women who: 

  1. Have a family history of birth defects
  2. Are 35 years or older
  3. Used possible harmful medications or drugs during pregnancy
  4. Have diabetes and use insulin
  5. Had a viral infection during pregnancy
  6. Have been exposed to high levels of radiation 

What does the triple screen test look for?

1.    AFP 

2.    hCG


The results are combined with the mother’s age, weight, ethnicity, and gestation of pregnancy in order to assess probabilities of potential genetic disorders. 

What do the triple test results mean?

It is screening test and not a diagnostic test

This test only notes that a mother is at possible risk of carrying a baby with a genetic disorder. 

The triple screen test is known to have a high percentage of false-positive results. 

What is meaning of ABNORMAL test results? 

Abnormal test results warrant additional testing for making a diagnosis.

Second triple screen followed by a high definition ultrasound. 

high definition ultrasound

If the testing still maintains abnormal results, a more invasive procedure like amniocentesis may be performed.