•Kneeosteoarthritis, chronic, degenerative, and progressive disease is characterized by not only structural modifications to primarily articular cartilage and the subchondral bone but also Hoffa’s fat pad, synovia, ligaments and muscles, leading to the concept of observing OA as a whole joint disease.

•It is estimated that the prevalence of knee osteoarthritis (OA) among adults 60years of age or older is 

•Approximately10% in men•

13%in women•Makingknee OA is one of the leading causes of disability in the elderly population.

•Perturbed equilibrium between anabolic and catabolic processes leads to the progression of OA and further structural changes

•The main mediators of cartilage metabolism are cytokines.

Synovitis is recognized as an important feature in patients with OA and has been associated both with symptoms and with structural progression.

•Oneof the main functional limitations in knee OA is the dysfunction of the quadriceps muscle, hamstrings and hip muscles.

•The main inflammatory cytokines are:• IL-1,•TNF-α•IL-6, •IL-8, •IL-17

•Geneticsplays an important role in the pathogenesis of OA, as observed in 40% to 80% of the hip or hand OA, but significantly less in knee OA.

•To date, 90genetic risk loci for the development of OA have been identified using genome-wide association studies (GWAS).

•The diagnosis of knee OA is typically based on the recognition of three symptoms •Decreasedfunction•Stiffness, and •Constantknee pain•And three signs •Limitedmovement, •Crepitus, and •Bony enlargement

•Radiographsare often used as the “gold standard” to confirm a diagnosis and to exclude other disorders. 

•Kneex-rays I anteroposterior and lateral views show joint space narrowing, osteophyte formation, subchondral degenerative cysts, subchondral sclerosis, and joint destruction.

•PRP or  Platelet-Rich Plasma is the result of the preparation of autologous plasma enriched with a platelet concentration. 

•Normal baseline concentration for blood platelets around 6%

•PRP technology concentrates platelet levels to around 94%  with the use of a centrifuge.

•Platelet concentration is 10 lakh/ml of PRP.

The progress of Knee Osteoarthritis to the advanced stage can be prevented by the newer Interventional pain treatments.

Platelet-Rich Plasma (PRP) therapy is the Newer Regenerative Therapy.

PRP provides a supra-physiologic concentration of Cytokines and growth factors in the affected area.

PRP promotes healing and faster recovery.

Platelet-Rich Plasma (PRP) therapy is effective in Stage 1 & Stage 2 OA Knee.

PRP is a Non-steroidal injection PRP that causes healing, PRP does not suppress the disease,

no need for Pain Killer.

A. We use the next-generation cooled Centrifuge

B. Dr.-PRP kit (US-FDA)

C. USG guided accurate sterile technique

Approved by US-FDA

Now in Kolkata.  Contact -9143067142