Pathogenesis of Diabetic foot
Multi-factorial and Complex
Neuropathy :- Damage to the Peripheral Nerves leads to Pain and later on complete loss of sensation in foot. This can cause injury to the foot which may go unnoticed and lead to ulcer formation, infection, gangrene and amputation.
Damage to motor nerves can lead to atrophy of muscles of foot and thereby change in bio mechanics of foot . This can cause increase in pressure on some parts of foot where thickening of skin( callous) , Ulceration and infection can occur.
Damage to autonomic nerves leads to decrease in sweating and formation of cracks on the heel of the foot which again can become a source of infection.
Vasculopathy : Peripheral arterial disease is very common in diabetic patients which reduces blood supply to the foot . This can make ulcer difficult to heal .
Immune dysfunction : Decreased immunity makes you prone to infection and biochemical changes in body.
Infection :- Diabetes makes your feet more susceptible to infection.
Prolonged Hyperglycemia contributes to all the above factors through different mechanisms so keeping your blood sugar in normal limits is very important. Diet and exercise and medications help you to control your blood sugar.
Ask your Doctor to examine your feet . Early treatment can prevent many serious complications.
Take care of your foot as you take care of your face.
Dr. Shrikant Bhoyar
General & Diabetic foot Surgeon
Ashokvan, Borivali East Mumbai
Tel : 9820136112