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My mom is suffering from microcytic hypochromic anaemia with evidence of mild hemolysis what to do we had done with the HPLC test and iron study it doesn't seem any sickle cell and thalessiama. What to do further now too confused 😕
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Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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It could be iron deficiency anemia
Visit hospital physically for further management and treatment plan
Next Steps
get usg abdomen and pelvis, lft, stool culture
Health Tips
Maintain healthy diet including spinach, lentils, tofu, fortified cereals, chickpeas
Take Tab FS+FA 1-0-1 for 30days
Tab Calcium 0-1-0 for 30days
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From these test we cannot evaluate much for sure from HPLC sickle cell is ruled out but for other cause u need few reports to be done
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Consult me for more guidance
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Hello, I understand your concern — anemia with mild hemolysis can indeed be confusing, especially when HPLC and iron studies are normal. Since microcytic hypochromic anemia with negative thalassemia and sickle cell results is present, we need to explore other possible causes such as:
Chronic blood loss (like occult GI bleeding or heavy menstrual loss)
Anemia of chronic disease (common in chronic infections or inflammation)
Early iron deficiency even before serum ferritin drops
Less common causes like sideroblastic anemia or enzyme defects causing mild hemolysis
Further evaluation with reticulocyte count, peripheral smear review, LDH, bilirubin (direct/indirect), Coombs test, and possibly a bone marrow study may be required if routine tests are inconclusive.
I can help review her reports in detail and guide you step-by-step on what to do next — including which investigations truly matter and what treatment should be started safely.
You can message me directly on WhatsApp at nine three two six zero two zero five three six for a personalized discussion and clear plan for your mother’s condition.
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Hematologist
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How are liver function tests ?
Look for spleen enlargement
Any fever .. rule out malaria ?
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probably an iron deficiency anemia.
Further management
USG abdomen to see organomegaly/
And send stool sample checked for any occult blood loss.
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It is most probably an iron deficiency anemia.
Next Steps
If concerned with hemolysis, take USG abdomen to see any spleen enlargement.
Also get a stool sample checked for any occult blood loss.
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Don't worry. Since your mother has microcytic hypochromic anemia with mild hemolysis but no thalassemia or sickle cell disease on HPLC, we need to look for other causes.
I advise doing peripheral smear, reticulocyte count, LDH, bilirubin (direct/ indirect), and Coombs test to check for autoimmune or hemolytic causes.
Also, repeat serum ferritin, CRP, and rule out chronic infections or blood loss. Based on the reports, we can decide if she needs bone marrow study or specific treatment.
For now, continue balanced diet, iron/ folate if advised, and stay in follow-up with reports.
Next Steps
Please get these tests done next - peripheral smear, reticulocyte count, LDH, indirect bilirubin, haptoglobin, Coombs test (Direct & Indirect), ferritin &
CRP.
These will help find the exact cause of anemia and mild hemolysis.
Once reports are ready, Send me to review it and next treatment advice
Health Tips
helpful tip will be
Ensure a balanced iron-rich diet (green
leafy vegetables, pulses, jaggery, dates). Keep hydration good and take medicines only as prescribed.
Regular follow-up with reports is important for proper diagnosis.
Word of Caution:
Don't start or continue iron tablets or injections without confirming low iron levels - excess iron can be harmful if stores are already normal. Avoid self-medication; follow up once test results are available.
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Need more history and reports ,examination
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kindly consult
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Consult with hematologist. Needed detailed history
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Further evaluation required to make a better clinical judgement
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kindly connect for consultation
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Consult with reports. Need to be evaluated.
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Give iron injection
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In stead of sitting at home and getting confused please consult a knowledgeable General Physician with all the reports. An appropriate treatment can be started. A long discussion which may be involved is not possible on Tele-consultation.
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Lab values are important. Cause of Micrositic Hypochromic anemias are to be ruled out. It might be just a nutritional deficiency or there might be bigger underlying causes.
Next Steps
Visit a general practitioner or internal medicine practitioner with CBC, Iron Profile reports
Health Tips
Donot depend on any over the counter suplement for treatment
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Autoimmune workup is left..Rule out chronic kidney disease..Then we can think of Mpn
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A haematologist will come to a diagnosis in this case , but the treatment would remain the same i e. Iron supplements. I dnt relate it to any malignancy. Still a detailed medical history might reveal some underlying medical condition. Kindly consult with me on 94 two six eight six 78 nine six.
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If you want to discuss your problem in more detail, feel free to message me on Whats App at nine one one nine two five five six nine nine for free detailed discussion
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Haem up caplets one at night for two months. ALWAYS BETTER TO CONSULT SUPERSPECIALIST LIKE HAEMATOLOGIST.
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Consult haematologist
Start orofer and folvite
Consult online
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Pls consult seven seven 3627 six four six two
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Dr. Vikram Pratap
General Physician
12 yrs exp
New Delhi
You should visit a physician or hematologist
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Dr. Sachin Bhiwaji Sanap
General Practitioner
7 yrs exp
Hingoli
need more information
kindly consult
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Dr. Shaikh Huzaif
General Physician
18 yrs exp
Aurangabad
Please consult
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Dr. Marini Vanitha
General Physician
12 yrs exp
Kakinada
Is there any iron deficiency.
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Dr. Manoj Kumar
General Physician
9 yrs exp
Dehradun
Need few more details
Kindly consult
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.