TYG INDEX-TRIGLYCERIDES TO GLUCOSE INDEX
First AuthorMUDDU SURENDRA NEHRU
Second AuthorMUDDU VENKATA RAMANA RAO
Third AuthorMURALI ANGAREKULADecember 10, 2023
Figure 1: homa health care center
1AbstractTYG INDEX: The abstract discusses the triglyceride glucose index (TYG-INDEX)as a cheap and easily accessible test that can be performed at any medical center.
TheTYG-INDEX is calculated by multiplying fasting triglycerides with fasting glucose anddividing the result by two. A TYG-INDEX value of 4.5 is considered indicative of in-sulin resistance. The abstract highlights the correlation of TYG-INDEX with dyslipi-demia, cardiovascular diseases, fatty liver, and insulin resistance. It also emphasizesthe significance of waist circumference, with a measurement above 85 centimeters in-dicating a correlation with high triglycerides and insulin resistance.[SMRMGR08]Figure 2: hiriThe abstract further mentions the TYG-glucose index, where a ratio above 0.8 sug-gests obesity and insulin resistance. The importance of early detection of insulin re-sistance and the recommendation for individuals to undergo a TYG-INDEX test isemphasized.[S ́INGFM+16]Keywords: triglyceride, glucose index,GLUCO-LIPO TOXICITY, TYG-index,fatty liver,JEL Classification: I12 - Health Behavior1 IntroductionThe triglyceride glucose index (TYG index) is a cost-effective test that can be performed atany healthcare center.2. The Triglyceride Glucose Index (TYG Index)This method involves collecting fasting blood samples for lipid profile testing and mea-suring fasting blood sugar levels.4. Correlation with Waist CircumferenceThe TYG index can also be correlated with waist circumference. Values above 85 cen-timeters indicate gluco-lipo toxicity and insulin resistance. Furthermore, a waist circum-ference to height ratio above 0.8 suggests obesity and high insulin resistance.[KSN+18]5. Waist Circumference to Height RatioThese indicators are crucial in assessing an individual’s risk for developing diabetesand other health complications such as heart attacks, strokes, kidney disease, and cancer.6. Hidden Diabetes Risk and Health ComplicationsIt is highly recommended that both the public and healthcare professionals from allspecialties consider getting a triglyceride glucose index test to assess insulin resistanceand potential health risks.[PAL+19]27. Recommendations for TestingBy identifying individuals with high TYG index values, appropriate interventions canbe implemented to prevent the onset of diabetes and its associated complications.2 Methodology3. MethodologyBy multiplying the triglyceride value obtained from the lipid profile test with the fast-ing glucose value and dividing it by two, a TYG index value is achieved. An index valueof 4.5 is considered normal, while any value above 4.5 indicates insulin resistance.3 resultsThe triglyceride glucose index (TYG-INDEX) is a cheap test that can be done at any center.The formula for TYG-INDEX is fasting triglycerides multiplied by fasting glucose dividedby two. Using a logarithmic calculator, the TYG-INDEX can be inferred. A TYG-INDEXvalue of 4.5 indicates insulin resistance.The TYG-INDEX is correlated with dyslipidemia, and it is an independent risk factorfor coronary artery disease (CAD), cardiovascular disease (CVD), and fatty liver. It is alsoassociated with insulin resistance and hidden diabetes.4 Discussion and ConclusionsIn conclusion, the triglyceride glucose index (TYG-Index) is a simple and inexpensive testthat can be done at any healthcare center. It is calculated by multiplying fasting triglyc-erides with fasting glucose and dividing the result by two. A TYG-Index value of 4.5 orhigher indicates insulin resistance, which is associated with various health conditions suchas dyslipidemia, cardiovascular disease, fatty liver, and hidden diabetes.[NGS ́IPD+16]Additionally, waist circumference is another important factor to consider when assess-ing insulin resistance. Individuals with a waist circumference greater than 85 centimetersoften have high triglycerides and insulin resistance. The TYG-Index can be used as a toolto identify gluco-lipo toxicity, with a normal cut-off value of 4.5.Furthermore, the TYG-Glucose Index, which is calculated by dividing the TYG-Indexby fasting glucose, can indicate obesity and the onset of insulin resistance if the ratiois greater than 0.8. A waist-to-height ratio greater than 0.5 is also indicative of insulinresistance.[SMRMGR08]Given the potential risks associated with insulin resistance, it is recommended thatindividuals consult their doctors and request a triglyceride glucose index test. This isespecially important for individuals with high waist circumference and other risk factorsfor insulin resistance. Early detection and intervention can help prevent the developmentof diabetes and cardiovascular complications.35 summaryIn summary, the triglyceride glucose index is a valuable tool for assessing insulin resistanceand identifying individuals at risk for various health conditions. Regular monitoring andearly intervention can significantly improve health outcomes.[ABHW20]The Homeostatic Model Assessment for In-sulin Resistance (HOMA-IR) is calculated usingthe formula:[SMRMGR08]HOMA-IR =Fasting Insulin×Fasting Blood Sugar405If the value is more than 2.3, it indicates in-sulin resistance.4The Triglycerides to Glucose Index (TyG Index) is calculated usingthe formula:TyG Index =Fasting Triglycerides × Fasting Blood Sugar2by using medical LOG calculators-LOGIN calculator and denomination 2 is inside the brackets thevalue is 4.55slno test name value range correlate with1 HOMA IR 2.3 more than 2.5 W.C.morethan85cms2 TYG INDEX 4.5 4.5 to 8.5 W.C. above 85 cms3 HOMA B less than33percent HOMA IR more than 2.3 diabetes4 C peptide 0.25 nmol less than 0.25nmol insulin deficit D.M.4 HDL less than 30 above 60mg/dl W.C. above 85cmsTable 1: metaboilism index6
References[ABHW20] Javad Alizargar, Chyi-Huey Bai, Nan-Chen Hsieh,and Shu-Fang Vivienne Wu. Use of the triglyceride-glucose index (tyg) in cardiovascular disease patients.Cardiovascular diabetology, 19:1–3, 2020.
[KSN+18] Sikandar Hayat Khan, Farah Sobia, Najmusaqib KhanNiazi, Syed Mohsin Manzoor, Nadeem Fazal, andFowad Ahmad. Metabolic clustering of risk factors:evaluation of triglyceride-glucose index (tyg index)for evaluation of insulin resistance. Diabetology &metabolic syndrome,
10:1–8, 2018.[NGS ́IPD+16] David Navarro-Gonzalez, Laura S ́ anchez- ́ ́Inigo, Juan ̃Pastrana-Delgado, Alejandro Fernandez-Montero, ́and J Alfredo Martinez. Triglyceride–glucose index(tyg index) in comparison with fasting plasma glu-cose improved diabetes prediction in patients withnormal fasting glucose: the vascular-metabolic cuncohort. Preventive medicine, 86:99–105, 2016.[PAL+19]
Kahui Park, Chul Woo Ahn, Sang Bae Lee, ShinaeKang, Ji Sun Nam, Byoung Kwon Lee, Jung Hye Kim,and Jong Suk Park. Elevated tyg index predicts pro-gression of coronary artery calcification. Diabetes Care,42(8):1569–1573, 2019.
[S ́INGFM+16] Laura Sanchez- ́ ́Inigo, David Navarro-Gonz ̃ alez, Ale- ́jandro Fernandez-Montero, Juan Pastrana-Delgado, ́and Jose Alfredo Mart ́ınez. The tyg index may predictthe development of cardiovascular events. Europeanjournal of clinical investigation, 46(2):189–197, 2016.
7[SMRMGR08] Luis E Simental-Mend ́ıa, Martha Rodr ́ıguez-Moran, ́and Fernando Guerrero-Romero. The product of fast-ing glucose and triglycerides as surrogate for iden-tifying insulin resistance in apparently healthy sub-jects. Metabolic syndrome and related disorders, 6(4):299–304, 2008.8