What are the other medicine available for IBS D treatment with visceral hypersensitivity. I have tried 1- librax, Ibset 2- Colospa X and Rifaxamin 400 mg 3 - Normaxin D 4 - Hyoscycomine. Only librax and Ibset have worked for me but it only worked for me for one month. Now it's not working anymore. Is there any other medicines available? I did my research there are valium and otilonium bromide. And I also heard about use of antihistamines for IBS. Please guide me. All my tests are normal. CBC, ESR,
CRP, Ultrasound, Fecal Calprotectine, Stool culture. All reports are normal. Please help if you know how to treat this life degrading curse. My symptoms are left abdomen discomfort and rectum discomfort and stools not properly formed.