Hi,
I had mild fibula avulsion two weeks back and now from yesterday have calf pain mildly when I stretch or move it. I checked here in UK and d dimer result is 5.0. The ultra sound is planned for tomorrow. I can't take blood thinners because I have mild haemophilia. Factor 8c deficiency. What to do?
Answers (15)
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Treatment decisions are based on the severity of the hemophilia (mild, moderate, or severe) and the presence of inhibitors (antibodies that neutralize the factor). Patients with mild or moderate hemophilia may tolerate anticoagulation more easily, but those with severe hemophilia require the strictest monitoring
concurrent Factor VIII replacement therapy or prophylaxis must be considered. Maintaining a safe minimum level of Factor VIII is necessary to prevent spontaneous hemorrhaging while using anticoagulants.
Next Steps
please consult a haematologist at UK
Get a Doppler of lower limbs
Drink plenty of water
Health Tips
Immediately reach out ER if you find any breathlessness
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D-dimer of 5.0 microgram/mL is significantly elevated and indicates the body is actively breaking down blood clots, which requires immediate investigation before undergoing any surgical procedure.
Do a Doppler to exclude Deep vein thrombosis.
Next, before surgery, correct the Factor 8c deficiency by raising it to 50-100% of normal.
Next Steps
In urgent cases, Desmopressin (DDAVP) is used to raise the factors.
D-dimer of 5.0 is significantly elevated, but D-dimer can be raised after recent trauma/fracture and does not by itself confirm DVT. However, calf pain occurring 2 weeks after a fibular avulsion injury warrants urgent exclusion of deep vein thrombosis.
Since you have mild Hemophilia A (Factor VIII deficiency), anticoagulation decisions are more complex and should be made jointly with a hematologist if DVT is confirmed.
My advice:
• Proceed with the scheduled venous Doppler ultrasound urgently (earlier if possible).
• Seek immediate medical attention if you develop increasing leg swelling, chest pain, shortness of breath, or coughing blood.
• Until Doppler is performed, maintain hydration and avoid prolonged immobility.
• Do not start or stop anticoagulants without specialist review.
If the Doppler confirms DVT, treatment is still possible in patients with hemophilia, often with factor replacement support and close hematology supervision.
Hi,
Proper evaluation and personalised advice are needed for your concern. A detailed consultation would be best to provide accurate guidance.
Feel free to consult me for further assistance.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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