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Allergic Reaction After Dog Bite (ARV)
On 13th Dec at around 3 PM, I had a dog bite.
At 4 PM, I received anti-rabies vaccine (both shoulders) and a tetanus injection.
At 5 PM, ERIG was injected locally at the bite site.
At 11 PM, I took Clavam 625 mg. Around 3 AM, I developed severe stomach pain, loose motions, and intense nausea.
At 11 AM, I was given Ondem and Drotin Plus injections. Within 30 minutes, I developed generalized allergic rashes all over my body (images attached). At 4 PM, I took XL-Mount, which reduced the symptoms, but mild redness persists. Does this allergic reaction or antihistamine intake affect the efficacy of the anti-rabies vaccine? Does this allergic reaction or antihistamine intake affect the efficacy of the anti-rabies vaccine? I have taken anti-vomiting and abdominal pain injections many times in the past, but never had such a reaction before. Why could this have happened now? Is this due to Anti Rabies Vaccine ?
Answers (16)
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This allergic reaction is most likely a drug-related hypersensitivity reaction and not due to the anti-rabies vaccine or ERIG. Anti-rabies vaccines and ERIG are inactivated and purified preparations and are not affected by allergic reactions elsewhere in the body. Also, taking antihistamines like XL-Mont does not reduce or interfere with the effectiveness of the anti-rabies vaccine in any way. Your rabies protection remains fully intact.
The timing and pattern of symptoms suggest that the reaction was more likely triggered by one of the medications, especially Clavam (amoxicillin-clavulanate) or the Ondem/Drotin Plus injections, which are known to occasionally cause delayed allergic reactions, even if they were tolerated in the past. Allergic reactions can develop suddenly at any point in life, even to medicines previously taken safely. The generalized itchy rashes appearing within 30–60 minutes of injection strongly point toward a drug-induced urticarial reaction.
The good response to antihistamine confirms this was an allergic reaction. Mild residual redness may persist for 24–72 hours and usually settles on its own. There is no need to repeat or restart rabies vaccination, and no dose has been neutralized or lost. Continue the remaining rabies vaccine doses as per schedule.
Next Steps
For now, avoid Clavam and inform future doctors about this reaction. If itching persists, a non-sedating antihistamine once daily for a few days is sufficient.
Health Tips
Seek urgent care if there is facial swelling, breathing difficulty, or throat tightness, which are rare but serious signs.
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Can help you with the next course of action and treatment plan. Kindly consult via whatsapp at nine zero two nine six zero zero four seven zero.
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This is urticaria. Possibly a reaction to one of the medicines, probably Clavum. Keep this recorded with you and avoid taking Clavum in future until extremely necessary.
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No, the allergic reaction will not affect the vaccine efficacy. The reaction most likely seems to be due to clavam or Drotin
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If you want to discuss your problem in more detail, feel free to message me on WhatsApp at nine one one nine two five five six nine nine for a detailed discussion
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Stop clavum , its clavum who gave u genralized rashes.
No reaction with arv, right or tt.
Continue montek lc one at night for 3to 5days.
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This is a medicine related allergy , not arv vaccine related.
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Its hives
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This is allergic reaction to a medicine. Do u have any medical history? Kindly consult with me on 94 two six eight six 78 nine six.
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Dr. Chaithra H
General Physician
5 yrs exp
Bangalore
Need not worry
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Dr. Laxmi Koppishetty
General Practitioner
8 yrs exp
Rajahmundry
Drug induced reaction
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Dr. Anuj Mothsra
General Physician
6 yrs exp
Jhunjhunu
Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Dr. Sajid Ali
General Practitioner
4 yrs exp
Kanpur
Montair L
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Dr. Vetsa Sri Krishna Chaitanya
General Physician
6 yrs exp
Rajahmundry
It's urticaria...Need a few more details please consult for further evaluation and treatment
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Dr. Surya Teja Akkineni
Internal Medicine
3 yrs exp
Vijayawada
May be not due to rabies vaccine may be related to other medications given
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Dr. Marini Vanitha
General Physician
12 yrs exp
Kakinada
It won't effect vaccine efficacy.
The allergic reaction to ondem or drotin plus.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.