On a routine test in June, my 59 y/o mother had slightly high serum globulins (4.7) and slightly high
calcium (10.3)
So we did the following tests :-
1- Serum protein electrophoresis - Came back normal with no M spike
2- Serum FLC -
Kappa - 33.1 (Ref- 3.3 to 19.4) - Slightly high Lambda - 18.1 - Normal
Kappa/Lambda ratio - 1.83 (Ref- 0.26 to 1.65)
Her calcium is back to normal now (without medications). At present, her calcium is 8.9, Hb is 12.5, serum globulin is 3,
creatinine is 0.75, urea is 25 and x rays of pain areas (cervical and thoracic spine and left shoulder) have shown arthiritis. So she doesn't have anemia, hypercalcemia,
kidney damage or bone lesions, as of now. However, her kappa chains are elevated and kappa/lambda ratio is slightly high. What is it pointing towards ? Could it be multiple myeloma ?