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My wife has ITP. It was first detected when she was a child. After taking steroids for some days, her platelet count became normal. Then for many years everything was fine. During her teenage years, her platelets dropped again but became normal within one week.
This time, after a few years, she had another ITP episode and her platelets dropped to 30–40 thousand. Due to heavy menstrual bleeding, she also lost blood. The doctor gave her Wysolone and Eltrombopag. Within 7–8 days, her platelets increased to 460,000.
My only question is:
Should we continue Eltrombopag or not?
Does continuing it increase the risk of clotting or blood clots?
When should it be stopped, or should it be continued?
Answers (21)
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Hello Practo User, use homoeopathic medications for your problem to get Instant and effective results.Its Curable, no need to worry about. Homoeopathic medicines plays Excellent role to treat Such problems in a hollistic way without any side effect.I suggest you to message me your complete history in private chat with all reports & details & Consult Online through Practo. I will guide you for holistic & effective Results with homoeopathy ! Take care !! Best Regards:)
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For now keep taking the current medicine as body is used to it but start taking Homeopathic treatment too
Gradually as the patient's condition improves the medicine will be decreased
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For now keep taking the current medications, along with it start your homeopathic treatment as well. Gradually we can alter the dosage . This is the best approach to handle the condition.
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Some more details required for proper treatment and diagnosis
You can consult me on practo either on eight seven five double zero two double seven one eight
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Hai,
ITP or Immune Throbocytopenia Purpura is an autoimmune disease, in which our body itself destroy the platelets within our blood leading to risk of bleeding.
Eltrombopag is the commonly prescribed medicines to stimulate bone marrow to produce more platelets.Its very expensive medicine with lot of side effects. Its safe to stop the medicine after regaining normal platelet level. Check platelet level once in a month.
Many patients are in my clinic with ITP and now enjoying healthier life without any acute attacks of ITP.
Homoeopathic medicines can correct ITP as these medicines influence positively to immune system. Homoeopathy will decrease the frequency of acute attacks of ITP.
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You can easily take an online consultation or book video consultation for further treatment guidance.
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Hi.As you know it is an Autoimmune disorder which causes destruction of platelets causing risk of bleeding. Homoeopathy is very effective in treating Autoimmune diseases.it helps in addressing the destruction of the cell by signaling our own body. It can help in controlling and can give best results. Wysolone is a steroid and eltrombopag is given to increase platelets. Both on long term will have it's own side effect. This is where Homoeopathy helps. You can take Homoeopathy medicine along with these medicines once better we can gradually reduce and stop these medicines. She can lead a healthy lifewith Homoeopathy medicine.To know more and for any other concerns you can call us or reach us online.
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Homoeopathic medicine is effective as a supportive therapy.
We can prevent relapsing of this disease condition with homoeopathic medicine.
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Not an expert on the subject of allopathic medicine so will not comment.
I can say homoeopathy is a better and safer option.
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ITP is a relapsing condition. Eltrombopag or steroids should not be stopped or changed without the hematologist’s advice, especially when platelet counts rise quickly. Dose adjustment is usually decided after repeat monitoring to avoid clotting risk.
Homeopathic treatment may be used as supportive, long-term care to help immune balance and reduce relapse tendency, but acute management should continue under a specialist.
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Consult online
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Take.
Caryca papaya. Q.
15 drops 3 times
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ITP is a relapsing–remitting condition, and treatment decisions are mainly guided by platelet count, bleeding symptoms, and overall risk factors. Eltrombopag is usually started to raise platelet counts to a safe range, not to keep them very high.
A platelet count of 460,000 suggests a very good response, and at such levels the dose often needs reassessment. Prolonged use of eltrombopag at high platelet counts can increase the risk of thrombosis, especially if counts remain persistently elevated.
In most cases, once bleeding is controlled and platelet counts stabilize above a safe level, the treating hematologist may reduce the dose or temporarily stop eltrombopag, with close monitoring. It should not be stopped or continued blindly without medical supervision.
Next Steps
I strongly recommend discussing dose adjustment or tapering with her hematologist and continuing regular platelet monitoring. Management needs to be individualized based on her clinical history and current status.
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Thank you for explaining your wife’s medical history in detail. From what you have described, she appears to have chronic relapsing ITP, with good responsiveness to treatment during each episode, which is a positive prognostic sign.
The recent rise in platelet count to 460,000 indicates a strong response to Wysolone and Eltrombopag. However, as you have rightly asked, this level is above the usual therapeutic target for ITP management.
Eltrombopag is a thrombopoietin receptor agonist, and its purpose is not to normalize platelets permanently, but to maintain them in a safe range (generally enough to prevent bleeding). When platelet counts rise excessively, there can be an increased risk of clotting, especially if continued without dose adjustment or close monitoring.
Therefore:
• Decisions regarding continuation, dose reduction, or stopping Eltrombopag must be taken only by the treating hematologist
• Regular platelet monitoring is essential
• Sudden stopping or continuation without guidance is not advisable
From a homoeopathic perspective, treatment does not aim to artificially raise platelet counts, but rather to address the underlying immune dysregulation that leads to recurrent drops. In chronic relapsing ITP, individualized homoeopathic management may be considered alongside or after stabilization, under proper medical supervision.
It is encouraging that your wife has repeatedly shown recovery between episodes. With a well-planned approach and careful monitoring, many patients are able to maintain long symptom-free intervals.
I would strongly advise continuing close follow-up with her hematologist and, if you wish to explore supportive or long-term constitutional management, doing so through a proper consultation rather than self-medication.
Wishing your wife continued stability and good health.
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Thank you for explaining the full history. Your wife has chronic relapsing ITP and has responded well to treatment this time. A platelet rise to 460,000 shows a strong response to Eltrombopag + steroids, but it also means the count is now above the safe therapeutic target.
Eltrombopag is a thrombopoietin receptor agonist. It is used to maintain platelets in a safe range (usually 50,000–150,000 for most ITP patients), not to push them into high normal levels. When platelets go very high, the risk of thrombosis (blood clots) does increase.
This is why in standard hematology practice:
• Dose is reduced when platelets exceed ~150k–200k
• Temporarily stopped if platelets go above ~400k
• Restarted later at a lower dose if counts fall again
So your concern is valid continuing full-dose Eltrombopag at 460k can increase clotting risk.
Next Steps
Please do not continue or stop on your own, but urgently consult the treating hematologist with the latest platelet report. Most likely they will:
• Taper or hold Eltrombopag
• Monitor counts weekly
• Adjust dose based on trend
Watch for warning signs of clotting
Seek immediate care if she develops:
• Sudden leg pain or swelling
• Chest pain or breathlessness
• Severe headache or vision changes
Health Tips
• Platelet overshoot is a known and manageable effect of Eltrombopag
• It does not mean danger if handled early
• Proper dose adjustment keeps treatment safe
Close hematology follow-up is essential at this stage.
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Dr. Sonal Ghadge
Homoeopath
16 yrs exp
Navi Mumbai
Homeopathic medicines
will surely help you .
consult online with me
during my clinic timings.
10 am to 2.00 pm
6.00 pm to 9.00 pm .
Health Tips
when you think platelets are reduced
give her in diet papaya, papaya leaf Syrup, kiwi,
dragan fruits.
To increase her platelets count.
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Dr. Faaizah Siddiqui
Homoeopath
4 yrs exp
Mumbai
Keep taking your current medicines. But also start homeopathic treatment. Then we can slowly reduce your old medicines over time until you don't need them anymore
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Consult me online
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Dr. Sameeksha Hemant Patil
Homoeopath
2 yrs exp
Nashik
Consult online through practo.
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Dr. Priya Sriramkeval Pal
Homoeopath
8 yrs exp
Mumbai
Sulphur 30C
Dose: 2–3 pills or 3–5 drops
Frequency: Once daily
Duration: 3–5 days only
Then STOP and observe for at least 7–10 days
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be in touch with doctor it is very important
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Dr. Deeksha Pandey
Homoeopath
3 yrs exp
Lucknow
I will answer this in a clear, medical, but practical way. Please note that this is general guidance, not a substitute for your treating hematologist’s decision.
Your wife appears to have chronic / relapsing ITP, given:
- First episode in childhood
- Long remission
- Relapse during teenage years
- Current relapse with platelets falling to 30–40,000, complicated by heavy menstrual bleeding
In this, treatment with:
- Wysolone (prednisolone) – to suppress immune destruction
- Eltrombopag – to stimulate platelet production
is standard and appropriate, especially when there is bleeding.
The rapid rise to 4.6 lakh (460,000) shows excellent responsiveness.
Eltrombopag is not continued at full dose once platelets overshoot.
Eltrombopag is not meant to normalize platelets to high levels, but to keep them in a safe range, usually:
- 50,000–100,000/µL
- Sometimes up to 150,000, depending on bleeding risk
A count of 460,000 suggests that:
- The drug has done its job
- Dose reduction or temporary stoppage is usually required
Continuing Eltrombopag Increase Clotting Risk it can — under certain conditions.
Eltrombopag is associated with a small but real risk of thrombosis (blood clots), especially when:
- Platelet count goes above 400,000
- There is prolonged use at higher doses
- Other risk factors exist (immobility, dehydration, estrogen therapy, smoking, obesity)
The absolute risk is still low ,Short-term elevation is usually reversible ,Doctors monitor counts closely to prevent
hematology approach:
1. Reduce or stop Eltrombopag once platelets rise above target
2. Continue close monitoring (CBC weekly or biweekly initially)
3. Gradually taper steroids
4. Restart Eltrombopag only if platelets fall again below safe levels
Many patients with relapsing ITP:
- Do not need lifelong Eltrombopag
- Use it intermittently, only during relapses
Very Important Points for You
- Do not stop or change the dose on your own
- Discuss the current platelet count with the treating hematologist immediately
Ask specifically:
- Should we reduce or stop Eltrombopag now ?
- What platelet range are we targeting?
- How often should we monitor CBC?
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Dr. Jyothi Kadkol
Homoeopath
26 yrs exp
Bangalore
Dear Sir,
I understand your concern very well. When ITP has been present since childhood and keeps relapsing at different stages of life, it creates constant fear—especially when platelet counts fluctuate widely and strong medicines are required. Your worry about continuing Eltrombopag and the risk of clotting is completely valid.
From your description, your wife appears to have chronic relapsing ITP, which is a well-recognized pattern. The recent drop in platelets to 30–40 thousand with heavy menstrual bleeding required immediate intervention, and the good response to Wysolone and Eltrombopag shows that her bone marrow function is healthy. However, a rise of platelets to 460,000 is more than what is required for safety. In ITP, the goal is not to push platelets very high, but to maintain them at a safe level to prevent bleeding.
Regarding Eltrombopag, it is usually used as a supportive drug, not a permanent solution for most patients. When platelet counts overshoot, doctors generally taper or temporarily stop the medicine while closely monitoring counts. Continuing it at the same dose when platelets are very high may increase the risk of clot formation, especially if used unnecessarily or for a prolonged period. Therefore, dose adjustment or withdrawal must be done carefully and individually, not abruptly and not without guidance.
Now coming to the role of homeopathy, which is very important in chronic and relapsing ITP. Homeopathy does not work by artificially forcing platelet production. Instead, it aims to correct the underlying immune imbalance responsible for platelet destruction. In my clinical experience, I have treated many ITP patients—both children and adults—where homeopathic constitutional treatment helped:
Reduce the frequency of relapses
Stabilize platelet counts naturally
Minimize or avoid repeated steroid use
Improve long-term immunity and overall health
Homeopathy is especially useful once the acute bleeding risk is controlled, as it can be safely continued long term without increasing clotting risk.
The key is individualized treatment based on the patient’s complete history, bleeding pattern, triggers, menstrual issues, emotional stress, and overall constitution. I would not advise stopping or changing allopathic medicines suddenly, but a planned, guided transition with proper monitoring can be considered under medical supervision.
Since your wife has a long history of ITP with repeated episodes, I would strongly recommend a detailed online consultation so her reports, past relapses, and current status can be reviewed and a safe, integrated plan can be made. With the right approach, many patients are able to remain stable and live a normal life without constant fear.
Regards
Dr jyoti kadkol
Health Global Homeopathy vijaynagar Bangalore
www.healthglobalclinics.com
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