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Double Marker Tst with intermediate risk
Hi, I am 35 ,1st preg natural conception. My NT scan and double marker test was done at 12 wks 5dy.
NT scan report - CRL 69.9mm, NT- 1.30mm, nasal bone present, all fetal anatomy visible and normal, T21 Adjusted risk 1:4737, Uterine Artery doppler mean PI 2.55, NT scan says normal with low aspirin dose advise.
Double marker Test - Intermediate risk
free beta hcg - 1.660 MoM
PAPP-A -0.341 MoM
T21 adjusted risk 1:578
Treating doctor has advised Ecosprin 150 and consultation with fetal med specialist and discuss for NIPT and Amneocentesis.
Could you suggest if it is really worrisome report.
Answers (11)
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The confirmation can't come at this stage. You should wait for further tests which will be done after about 6 weeks. NIPT at this stage will also give doubtful results. Amniocentesis is not possible at 12 weeks. Chorionic villous sampling can help in the diagnosis but it can also lead to an abortion.
So you should wait for further tests after 6 weeks. Then things can be clear.
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Pls connect for online consultation and advice
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Dr. Nirav Jetani
Gynecologist
11 yrs exp
Vadodara
Go for NIPT
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Dr. Kinnari Amin
Gynecologist
12 yrs exp
Ahmedabad
Double marker has low sensitivity and specificity
Go for NIPT
If NIPT shows low risk then noth to worry
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Dr. Hitendrasing Patil
Gynecologist/Obstetrician
6 yrs exp
Pune
Hello, even if you go for NIPT, if comes positive, for confirmation you have to go for Amniocentesis again. Let's discuss this in very detail. I have few patients just like you.
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Dr. Parru Singh
Gynecologist/Obstetrician
8 yrs exp
Lucknow
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Dr. Vijaya Gupta
Gynecologist
21 yrs exp
Chandigarh
The intermediate risk in double marker test needs further evaluation
Double marker is only a screening test
So is nipt
you need a diagnostic test aminocentesis
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Dr. Sayali Dhalwade
Obstetrician
15 yrs exp
Pune
NIPT or amniocentesis is required
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Dr. Neha Vashisth
Obstetrician
12 yrs exp
Jaipur
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.