Hello doctors,
When taking blood test anytime, WBC count and platelets is always high.
Recent blood test result:
Wbc- 14.3
Platelet- 470
Consulted multiple doctors but it's told no issues and no treatment is needed now. But I am still worried on it.
Please suggest what can be done.
Answers (12)
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For a 29-year-old female with consistently elevated WBC (14.3 × 10⁹/L) and platelet count (470 × 10⁹/L), based on the Harrison’s Manual of Medicine:
Interpretation:
Leukocytosis (WBC >11 × 10⁹/L):
Mild elevation like 14.3 is usually due to:
Chronic infections (e.g., TB)
Chronic inflammatory states
Stress or smoking
Drug effect (e.g., steroids)
Myeloproliferative disorders are rare but should be ruled out if persistentHARRISONS-Manual-of-Med….
Thrombocytosis (Platelets >350 × 10⁹/L):
If platelet count is persistently >450 × 10⁹/L, consider:
Reactive causes: infection, inflammation, iron deficiency, recent surgery, vitamin B12 deficiency, recovery from marrow suppression
Primary thrombocytosis (e.g., essential thrombocythemia) is a diagnosis of exclusion, usually when count >500 × 10⁹/L with no reactive causeHARRISONS-Manual-of-Med….
Next steps:
Repeat CBC in a few weeks to confirm persistent elevation.
Peripheral smear to look for reactive vs clonal features.
Rule out: iron deficiency, infection, inflammation.
If persistent and unexplained, bone marrow biopsy and JAK2 mutation testing may be considered to evaluate for a myeloproliferative disorderHARRISONS-Manual-of-Med….
There is no immediate danger if asymptomatic, but periodic monitoring and basic workup are advised.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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