Gallbladder (GB) stones, also known as cholelithiasis, develop when the components of bile become imbalanced, leading to the formation of solid deposits inside the gallbladder. The most common cause is excess cholesterol in bile, which crystallizes and gradually forms stones. Other causes include increased bilirubin levels, reduced emptying of the gallbladder, bile stasis and gallbladder inflammation. Risk factors include obesity, rapid weight loss, a high-fat and low-fibre diet,
diabetes, pregnancy, hormonal changes, increasing age, family history and
liver-related disorders. Gallstones may remain asymptomatic or cause right upper abdominal pain, nausea, vomiting and indigestion, particularly after fatty meals.
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