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Triple Marker Positive with 1:182 ratio
Hello Doctors,
I am a 33yr old female. This is my second pregnancy. My NT scan was normal but triple marker test was positive with 1:182 ratio positive screening for Trisomy 21. The matter of concern for me is that the value of unconjugated estriol (uE3) is extremely low which is 0.13 ng/mL at 14 weeks 6days pregnancy also my Triple Marker was done twice by the lab to rule out any discrepancy. How reliable is Triple Marker also can it show false results as it was done at 14 weeks while it's suggested to get it done after 16 weeks. Also mentioning the MoM values for your reference
AFP 0.79
Ue3 0.51
HCG 1.46
Kindly suggest does these MoM are too low/high or the pregnancy could be healthy with these values.
Answers (5)
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NIPT is best non invasive test to clear ur doubt
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Dr. Pratibha P S
Gynecologist
10 yrs exp
Bangalore
get nipt
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Dr. Neha Vashisth
Obstetrician
12 yrs exp
Jaipur
Connect
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Dr. Manoj Kumar
Obstetrician
20 yrs exp
Amritsar
Hello !
Triple marker test can be false positive also & not that reliable. Quadruple marker test can be done at 16 weeks Gestational age .
But
Rather then going for marker test, you should go for NIPT test ...
In case of slightest doubt I will suggest NIPT
which is simple & Reliable .
In case if NIPT also ... comes Abnormal
then AMNIOCENTESIS is to be done for definitive diagnosis.
Next Steps
NIPT to be done.
Health Tips
Don't worry, These marker test show false result with many patients...
iIn case of any doubt please connect...
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Dr. Prateeksha B S
Obstetrician
7 yrs exp
Bangalore
Triple marker test is just 60-70 % reliable
So in case of doubt better to do a NIPT test
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.