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Chances of genetic disorder
If someone marries in 4th generation of same family i.e. boy's grandfather mother and girl's grandfather mother are real sisters. Is there any chance of genetic disorder passing on to future generation.
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Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Marrying within the extended family—even several generations apart—slightly increases the statistical probability that both partners share common recessive genes inherited from their shared ancestors.
Next Steps
Preconception Genetic Counseling: A formal session with a genetic counselor can map out a detailed pedigree chart to evaluate the exact coefficient of inbreeding.
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Marrying within the same extended family, even a few generations apart, does raise the chance that both partners carry the same recessive gene, which can surface as a genetic condition in a child only if both parents happen to carry it.
Next Steps
The actual risk depends on how closely related you are and whether any conditions run in either family, so a preconception genetic counselling session with blood tests can give you a real picture instead of a guess.
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This isn't a reason to assume a problem will happen, most children of related couples are healthy, but please consult your doctor or a genetic counsellor beforehand.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.