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Bhcg level 3.95 on day 13 in IVF ICSI
Hi doctor
I transfer IVF- ICSI for first time on 4th Dec 2025 with 2 FET blastocyst.
After day 13 Beta HCG test done on 16th Dec 2025 which was 3.95.
Repeat Beta HCG test done after 48 hours which was 2.19. It's negative I know.
I want to know the possible reason why it failed?Was my implantation succesful? Means it's implant but not growing?or it failed to implant?
Also what I should do next time for better result?
I have only 1 blastocyst left.before transfer what I do? Kindly advise doctor.
Answers (11)
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There are no "possible reasons". Every attempt at IVF-ET comes with about 40-50% failure. Make an attempt again after about 3 months. It may succeed.
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Success rate for each cycle is 30-40%. Your fertility specialist is the best person to discuss cause of failure and how to improve chances next time.
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Dr. Pratibha P S
Gynecologist
10 yrs exp
Bangalore
you can get endometrial biopsy once
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Dr. Kinnari Amin
Gynecologist
14 yrs exp
Ahmedabad
Discuss with your treating doctor
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Dr. Rutuja R Athawale
Infertility Specialist
19 yrs exp
Bangalore
1) Why it failed? Need to know the grade of blastocyst and have u done Pre genetic screening of embryo ? What is your age if ur age is above 35yrs then genetic anomalies are common leading to implantation failures.
2) implantation was successful or not we need to see if u were on Inj HCG 2000/5000 IU then it is not implanted but if u have not taken HCG injection post transfer then it had implanted giving u biochemical positive result but it didn't grow further.
3) To plan further i would like to know ow ur previous history whether u had similar losses before or any other natural conception losses etc and then we can plan properly further... plus single blast with genetic screening done if ur transferring success rate with single blast is 40%.
Next Steps
please look in your endometrial lining thickness , vascularity, infection, 3D of the uterus etc before transfer if required u can plan.
All the best 👍
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take particle result oriented decisions and not in emotional one
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Dr. Sravya Naramchetti
Gynecologist/Obstetrician
8 yrs exp
Visakhapatnam
Your doctor has been following you since the beginning, im pretty sure they would be the better judge
Multiple reasons will be there for not being sucess
Like the oocyte quality sperm quality, overall blastocyst quality, endometrium etc
Discuss with your doctor if you have to undergo one more cycle of oocyte retreival? And then transfer
Next Steps
Its very stressfull when your trying for pregnancy, my only advice is to stay clam and stress free as possible it will get better
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Dr. Alisha Goyal
Gynecologist/Obstetrician
7 yrs exp
Gurgaon
You need consultation for proper counselling
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Dr. Aastha Jain
Gynecologist
6 yrs exp
Ajmer
- *Why it failed*: Possible reasons are embryo quality, uterine lining issues, or hormonal factors, and embryo selection.
Next Steps
What to do before next transfer: Discuss with your doctor about improving lining preparation, hormonal support
Health Tips
connect
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Dr. Prateeksha B S
Obstetrician
7 yrs exp
Bangalore
It needs detailed evaluation
Blastocyst is a very good quality
But the uterine lining and implantation should also be favourable
It has failed to implant
Next Steps
consider ovum pick up as only one blast is left
Health Tips
cumulative effect will be there so subsequent cycles the chances of pregnancy increases
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Dr. Garima Singh
Reproductive Endocrinologist (Infertility)
8 yrs exp
Delhi
There are several reasons of implantation failure. Connect for more discussion
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Dr. Neha Vashisth
Gynecologist
14 yrs exp
Jaipur
Connect
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