IBS that doesn't respond to allopathic treatment after 5 years, combined with rapid weight gain in a high-stress sales job, suggests that lifestyle and stress are major drivers that medicines alone can't fix. Chronic stress dysregulates the gut-brain axis and raises cortisol, which directly promotes abdominal weight gain and worsens IBS symptoms. A sedentary work pattern in sales also contributes to sluggish gut motility and fat accumulation.
Next Steps
A low-FODMAP diet trial for 4-6 weeks often gives significant relief in refractory IBS. Stress management â regular exercise, adequate sleep, and addressing work stress â is equally important as any medicine. A gastroenterologist evaluation is recommended to rule out other causes. Please consult me directly on Practo for a detailed evaluation.