Sir/Ma'am,
It has been observed that my ankle get swell. I did KFT and it has been found that uric acid increased for that i m taking Furic 40. Further, i m taking olisur f5 from past one year and lonazep 0.25 from 3 months. What is the reason behind ankle swelling. Last year i did holter ,ecg and echo and all comes normal.
Is this the size effect of olisur f5(ankle swelling)??
Answers (11)
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Uric 40 can cause swelling, but first share details, how much was your uric acid, whether swelling is over one ankle or both, is it pitting on touching and or painful, is it continuous or intermittent?
With above details, I can guide you and help you.
I can definitely help you over this being a general physician
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ankle swelling (peripheral edema) in your case may relate to several possible causes:
1. Uric Acid Elevation (Hyperuricemia)
Gout due to hyperuricemia can cause joint pain and swelling, often in lower extremities.
However, gout attacks usually cause painful, red, hot joints rather than just soft swelling.
2. Medication Side Effects
Olisure F5 contains olanzapine (atypical antipsychotic), known to cause:
Peripheral edema as an uncommon side effect.
Mechanism may involve vasodilation or fluid retention, not necessarily cardiac or renal in origin.
Clonazepam (Lonazep) is less commonly associated with edema, but it may additively contribute via CNS or hypotensive effects.
3. Other common causes to consider:
Renal dysfunction: Already being monitored through KFT.
Cardiac causes: Less likely given normal ECG, ECHO, Holter.
Hepatic causes: Consider if any abnormal LFT or symptoms like fatigue/jaundice.
Next Steps:
Consider switching or tapering olanzapine under psychiatric supervision if the edema worsens or persists.
Rule out proteinuria, serum albumin, and repeat KFT to reassess renal contribution.
Reduce dietary salt intake and elevate legs periodically.
Reference: Harrison’s Manual of Medicine, 20th Ed – Edema causes and drug-induced edema.
MARK HELPFUL 🙂🙂🙂
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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