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Dual Marker Test is Positive
My wife is 13 week pregnant. In NT scan, Nuchal fold was found to be 2.30mm. Doctor suggested DUAL MARKER test to check baby health. Test results says " Screening test has a probability of 1:122 for Down's Syndrome. Screening Test is positive"
Trisomy 21 is 1:122
Trisomy 18 is 1:1759
Trisomy 13 is 1:1593
Nasal bone is about 1.97mms
Doctor has suggested "Amniocentesis" for further investigation.
Please advice. Does all these means there is definite chance of Down Syndrome or this is just a possibility. Doc says since Nasal bone formation is good, probably baby will also be fine but since DUAL MARKER result says high risk hence we have to do Amniocentesis.
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Answers (5)
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This test just gives you probability .
She is in high risk category .
If you want confirmation then amniocentesis is the option otherwise you can go for NIPT test which is 99percentage sure .
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Dr. Mina Bulchandani
Gynecologist
23 yrs exp
Hyderabad
Nothing to worry, this is just possibility not confirmatory, please go ahead for amniocentesis, avoid stress.
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Dr. Nidhi Sharma
Gynecologist/Obstetrician
19 yrs exp
Chennai
Chances of Down’s are only 1 in 123, that is less than 1%
Next Steps
Relax just take care
Health Tips
Do an amniocentesis but if money is not a constraint please do NIPT which is much safer and accurate
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Dr. Jay Desai
Obstetrics & Gynecology
7 yrs exp
Pathanamthitta
Hello there,
The interpretation of your report is as follows
Out of 122 women with similar factors, 121 will have normal baby
Only 1 will have chnc of down's baby.
Same goes way for trisomy 18/13 ratio.
So cut off being 1:250, your risk is increased.but that doesn't diagnose baby as downs
To rule out the high risk , it's better to confirm the report by a diagnostic test.
That's why amniocentesis is advisable
Next Steps
follow doctors advise
avoid stress and anxiiety
Health Tips
continue iron calcium supplements
get amniocentesis done.
also can try for NIPT/NIPS
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Dr. Swarupa Jaiswal
Gynecologist
5 yrs exp
Guwahati
Dual marker hast is just a screening test. Its sensitivity is about 50% only. That means the test can give false result in 50% of cases. To confirm will have to do amniocentesis.
And the NT is normal.
I had a patient with same kind of report. Her amniocentesis came out normal and she delivered a healthy baby.
So stay positive and hope for best.
Next Steps
Should do amniocentesis from a good centre and must consult fetal medicine expert.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.