I had gbs , acute pancreatitis and some sort of ibd all within last 1.5 years. Biopsy of colon:
The lymphoid aggregates in biopsies I to V show an admixture of CD20 positive B cells and CD3, CD5 and
CD7 positive T cells with a mild predominance of T cells with low proliferation index. The lymphoid
follicles show prominent intact germinal centres positive for bcl6, CD20 and CD10 with high proliferation
index with occasional follicles showing disruption by the marginal zone cells and T cells. The lymphoid cells
are negative for Cyclin D1.
Impression Review of slides [H &E and IHC slides] shows - - Evidence of active
colitis with aphthous ulcers, cryptitis and multiple crypt abscess and occasional small histiocytic
aggregates. - Hypertrophied lymphoid tissue with follicle formation and prominent mantle / marginal
zones. - Nodular lymphoid aggregates composed of admixture of T and B cells with mild predominance of T cells, evidence of epitheliotropism and low proliferation index.
Answers (3)
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Reports s/o B cell lymphoma
Will be requiring further tests and reports to discuss further plan
Can meet me Dr Akash khandelwal a trained Hemato oncolgist online for further discussikn
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