My mother has polycythemia vera since 6years. Jak 2 positive. Taking hydroxyurea 500mg daily and warf 2 mg . Is this pv will transform into leukaemia or myelofibrosis in future?
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History noted - JAK 2 positive PV
JAK2-positive PV patients have a higher risk of developing myelofibrosis and acute leukemia than those who are JAK2-negative. Still the risk is usually less than 1% per year for Jak 2 positive cases to progress. Not all cases will progress .
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