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Having trouble with weight
Hello Eceryone I am a 27-year-old female struggling with weight loss. My current weight is around 75 kg and height is 163 cm. Even when I follow a strict diet, avoid sugar/outside food, and try to maintain a calorie deficit, I find it very difficult to lose weight and regain easily. I have hypothyroidism and I’m concerned there may be underlying hormonal issues like PCOS/PCOD or insulin resistance affecting my weight. I also struggle with cravings and appetite control.
Could you please advise what tests I should do (thyroid levels, hormones, insulin etc.) and whether treatment options like GLP-1 medications (semaglutide/tirzepatide) would be appropriate and safe for my case?
Answers (11)
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You have to check your thyroid profile
Get a diabetic testing done Hb1Ac fasting and postprandial values
PCOS can be easily detected by doing a pelvic scan
Before getting all this done it might not be wise to start on GLP 1 like semaglutide or OZEMPIC AS these drugs are with their fair share of side effects ... nausea vomiting constipation .. hating to eat food ... alongside weight liss and fat loss there will DEFINITELY BE MUSCLE LOSS AS WELL
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Go to obesity clinic for proper guidance
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Yes, helps
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Avoid fried and spicy food
Water intake more
Green leafy vegetables more
Fiber meal
Walk
Do connect and consult
Will help you
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Your concern about underlying hormonal factors is very valid. Hypothyroidism, even when being treated, is a significant barrier to weight loss if the TSH is not optimally controlled (target TSH for weight management is ideally 1â2 mIU/L, not just 'within normal range'). Additionally, PCOS and insulin resistance are extremely common in young women with hypothyroidism and together create a perfect storm for stubborn weight gain despite calorie restriction. Regarding GLP-1 medications like semaglutide (Wegovy) or tirzepatide (Mounjaro): at a BMI of 28.2 with hypothyroidism as a comorbidity, you do meet the threshold criteria for these medications, and they can be effective. However, they work significantly better when thyroid function is first optimised, and they do have side effects (nausea, GI symptoms) that need monitoring. They should be started only after a thorough hormonal evaluation.
Next Steps
Get these tests first: TSH + Free T4 (to assess thyroid control), fasting insulin + HOMA-IR (for insulin resistance), HbA1c, LH:FSH ratio, testosterone, DHEA-S, prolactin, Vitamin D, and a pelvic ultrasound (to rule out PCOS). Based on the results, a doctor can determine whether dose adjustment of thyroid medication is needed and whether GLP-1 medication, metformin, or other treatment is appropriate. Focus on strength training rather than cardio for best results with hypothyroid weight gain. Please consult me directly on Practo for a detailed evaluation.
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Proper evaluation and personalised advice are needed for your concern. A detailed consultation would be best to provide accurate guidance.
Feel free to consult me for further assistance.
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kindly do connect and consult with me for better treatment plan and advice on your case via PRACTO app
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Better if you consult with endocrinologist.
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Dr. Vetsa Sri Krishna Chaitanya
General Physician
7 yrs exp
Rajahmundry
Need a few more details please consult for further evaluation and treatment
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Dr. Anuj Mothsra
General Physician
7 yrs exp
Jhunjhunu
Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.