HPLC report of bride is normal. But groom HPLC report is...HbF -2. 5%, HbA2-2. 20%, HbA- 84.40% ... ... Groom is 32 years old... Healthy... No other problems...is HbF significantly elevated??? Would there be any problem if the marriage happens??? What kind of health or genetic condition does the groom have... Groom's CBC report is normal.This is urgent.. Please reply..
Answers (10)
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**Response:**
**Answer:**
The groom's HPLC report shows mildly elevated HbF (2.5%) with normal HbA2 (2.20%) and normal CBC. Here's what this means:
1. **Interpretation:**
- HbF levels are slightly above normal (typically <1% in adults)
- This pattern could suggest:
* Benign hereditary persistence of fetal hemoglobin (HPFH)
* Very mild beta-thalassemia trait
* Normal variation
2. **Health Implications:**
- No immediate health concerns for the groom
- No impact on fertility or marital life
- Normal life expectancy
3. **Genetic Considerations:**
- Since the bride's report is normal, risk to future children is minimal
- Extremely low chance of having children with thalassemia major
- Genetic counseling can provide complete reassurance
**Next Steps:**
- No urgent action needed
- Optional confirmatory tests:
* Repeat HPLC after 3 months
* Genetic testing if desired for complete certainty
**Consultation:**
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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