Hello,
Your
TSH has decreased from 3.87 to 0.26 mIU/L after increasing Thyronorm (levothyroxine) from 88 to 100 mcg daily.
This suggests that 100 mcg may be slightly more than your current
thyroid hormone requirement, although your free T4 level is needed for proper interpretation.
Since you are anti-TPO positive and actively trying to conceive, maintaining appropriate thyroid function is particularly important.
Before pregnancy, a TSH target of approximately 0.5â2.5 mIU/L is commonly preferred in women receiving levothyroxine.
Your current TSH is mildly suppressed, but this is generally not an emergency. The dose should be reviewed rather than making an abrupt change yourself.
Next Steps
Consult an endocrinologist to review your levothyroxine dose. Check
TSH and free T4 to assess whether the current dose is excessive. Your physician may consider a small dose reduction, but the exact dose cannot be determined safely from TSH alone. Repeat
thyroid function testing approximately 6 weeks after any dose adjustment. Continue taking Thyronorm consistently on an empty stomach, ideally 30â60 minutes before breakfast. Keep
calcium and iron supplements at least 4 hours apart from levothyroxine.
Health Tips
My recommendation: Your
TSH of 0.26 suggests possible mild over-replacement. A small dose adjustment may be appropriate, but this should be determined after reviewing your free T4 and clinical history. Do not stop Thyronorm abruptly, especially while planning pregnancy. If pregnancy is confirmed, contact your endocrinologist immediately, as
thyroid hormone requirements commonly increase during pregnancy. However, given your currently suppressed TSH, any dose increase should be individualised. Thyroid function should generally be monitored every 4 weeks during early pregnancy. With appropriate dose adjustment and monitoring, women with autoimmune hypothyroidism can have healthy pregnancies. Wishing you good health!