🧠 My Opinion (As a Psychiatrist): From what you’ve shared, your sister is showing significant signs of emotional burnout and depressive symptoms—likely triggered and perpetuated by unresolved interpersonal conflict, invalidation, and emotional isolation. Her inability to attend classes, loss of motivation, hopelessness, low self-worth, and withdrawal from food and activities are clinical red flags that should not be ignored. Such symptoms, especially when persistent, could point toward an adjustment disorder or even major depressive episode, especially if they're affecting her day-to-day functioning and thought patterns negatively. Emotional invalidation from her social circle may be intensifying her distress, making her feel unseen and unvalued.

Relationship problems can be difficult to manage. Especially if there is no proper outlet to your problems. Progress starts with letting it out in a professional and safe space. Taking psychotherapy under a professional can have a great impact. Happy healing!

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Hi.. will need further history regarding the same to advise appropriately. She could be probably depressed. Consult online for further evaluation and management

Take some therapy

If a person's behaviour is impairing personal, social, education life , it indicates that some management Should be started. As you described there is an ongoing stressor, adjustment disorder can be considered. I will suggest that, plan a consultation so that more detailed assessment can be done in terms of symptoms, duration, associated symptoms and further management plan as per assessment