What you describe - medication fatigue, persistent low mood, irritability, loss of motivation, poor concentration, social withdrawal and constant worry about the future - are core features of depression with anxiety. These feelings are real and treatable, but they often need a fresh review of treatment (both medication and therapy) and short-term practical support to stabilise.
Next Steps
Please contact your treating psychiatrist as soon as possible and tell them you're struggling with medication adherence and worsening symptoms - they may adjust medications, simplify the regimen, or suggest safe alternatives. Begin regular counselling/ psychotherapy (CBT, behavioural activation, or supportive therapy) to work on motivation, rumination and coping skills - you may consult with me for counselling support. If you ever feel like harming yourself or think you might act on these thoughts, seek emergency help right away (call 108/112 in India or your local emergency number) or contact a suicide/crisis helpline immediately.
Health Tips
Try very small, manageable steps each day (one 10-minute walk, one short household task) to rebuild momentum. Use grounding and paced-breathing when panic or rumination rises (inhale 4 - hold 2 - exhale 6). Maintain basic sleep and meal routines, limit stimulants (caffeine, late screens), and reach out to one trusted person and tell them you're having a hard time. Keep a simple mood log (time, trigger, what helped) so you and your clinician can spot patterns quickly.