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B12 and folate deficiency
My serum value B12 226 pg/ml, past 1
year ago had 162 pg/ ml so doctor prescribed
3 re-nerve plus injection. My current MMA -
481, active b12- 32, Homocysteine >50, folate -
1.19, ferritin serum 32.3. I have
been facing floating sensation for past 2 years
reduction in libido, pins and needles pain in
palms and feet and some time severe pins and
needle pain in penis after ejaculation
Already visited many doctors almost all of them are telling that my blood report is normal but my symptoms are not getting improved come and goes not able to judge what
is happening. Do I have b12 folate deficiency ? Please help 🙏
Answers (20)
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Homocysteine >50 — this is very high (normal is under ~15). Homocysteine rises when either B12 or folate is insufficient, because both vitamins are needed to clear it. A level this high strongly suggests significant deficiency of one or both.
Folate 1.19 — this is low (normal usually >3-4 ng/mL), confirming folate deficiency is also part of the picture.
Ferritin 32.3 — low-normal, borderline low iron stores, which can independently contribute to fatigue/lightheadedness.
Next Steps
Active follow up and detailed consultation
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Not only this vitamin deficiency
May cause other vitamin also deficient
Kindly consult for more details
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Yes, functional B12 deficiency confirmed — high MMA/homocysteine + low active B12 despite "normal" serum B12 explain your nerve symptoms. Needs proper IM B12 loading (not oral), plus nerve conduction study if symptoms persist. Book a private consult to plan the injection protocol.
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B12 is 32 , its severe deficiency. You need to take injection again.
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