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Abdominal tb and jaundice
My sister was on ATT for more than a month. She took AKT 2, Pyrazinamide 750mg (2 tab), Ethambutol 800 and Benadon. From 29th September doctor replaced AKT 2 with RCinex (450+300). After taking r cinex for 2 days, she developed itches, rashes and yellow eyes. Dr changed back to AKT 2 3 days before. Day before yesterday, LFT was done (included the report) which indicated jaundice. Today dr gave injection for jaundice and stopped ATT for a week. He replaced the tablets with moxif 400 and Combutol 600. I have uploaded the prescription.
Also he's denying that it was caused by r cinex though everything started after that tablet. Before that, she was improving significantly. Please tell if his steps are right. Because I've heard if tb medicines are stopped, mtb will develop resistance.
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Dr. Yogesh Kumar Sehrawat
Consultant Physician
11 yrs exp
Delhi
This is a case of att induced hepatitis, it's usually caused by rifamipicin or pyrazinamide in the att regimens. There are two ways to deal with this, either stop all the att and start again one medicine at a time when lft comes normal. Other way is to start levoflox or cipox along with ethambutol. Whatever the treatment you are saying is going on, it's seems not in tuning with the guidelines. Amikacin can also cause kidney issues so better check kidney function tests regularly, if Amikacin is required for the patient, though it's not advised even after att induced hepatitis. And mdr tb doesn't develop like this so don't worry if att is to be stopped or restarted.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.