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Tenderness in left breast

My wife has started to feel tenderness and mild pain in her left breast since last 2 days. She has never felt such pain before during her regular periodic cycle. We are trying to conceive for some time but the pregnancy tests are showing negative results. Is it a sign of pregnancy & when should we perform tests again.
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Dr. Hithysh BM
General Physician 2 yrs exp Bangalore
Hello during menstruation women tend to have breast discomfort like pain etc You can do next test only when she misses her period for further evaluation and treatment consult obg specialist.
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